Results 91 to 100 of about 151,112 (335)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Mechanistic study on the susceptibility of Staphylococcus aureus to common antimicrobial preservatives mediated by wall teichoic acids

open access: yesApplied and Environmental Microbiology
Staphylococcus aureus is a common food-borne pathogen that easily develops resistance to antibiotics and antimicrobial peptides partly because of wall teichoic acids (WTAs), the peptidoglycan-anchored polymers important for cell physiology.
Xia Wu   +4 more
doaj   +1 more source

Optimizing the Antimicrobial Activity of Tasmanian Pepper Leaf Oil Emulsion as a Natural Preservative for Capsicum

open access: yesProceedings, 2020
: The aim of this study was to produce and optimize Tasmanian pepper leaf (Tasmannia lanceolate; TPL) oil contained emulsion using sonication and Response Surface Methodology (RSM).
Maral Seidi Damyeh   +3 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Tolerability in Glaucoma Patients Switched from Preserved to Preservative-Free Prostaglandin-Timolol Combination: A Prospective Real-Life Study

open access: yesClinical Ophthalmology, 2022
Sonja Jandroković,1,2 Sania Vidas Pauk,1 Dina Lešin Gaćina,1 Ivan Skegro,1,2 Martina Tomić,3 Sanja Masnec,1,2 Tomislav Kuzman,1,2 Miro Kalauz1,2 1Department of Ophthalmology, University Clinical Hospital Center Zagreb, Zagreb ...
Jandroković S   +7 more
doaj  

The Moisture Content Effect on Full Cell Process of Bamboo Preservation [PDF]

open access: yes, 1990
The retention, penetration and also the distribution of CCA preservative in three different conditions (fresh, partially dry and dry) of bamboo of Gigantochloa scortechinii were studied.
Permadi, Pipin
core  

Tantilla annulata [PDF]

open access: yes, 1985
Number of Pages: 1Integrative BiologyGeological ...
Wilson, Larry David
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Scientific Opinion on the safety and efficacy of ammonium formate, calcium formate and sodium formate when used as a technological additive for all animal species

open access: yesEFSA Journal, 2015
This opinion concerns the re‐authorisation of ammonium, calcium and sodium formates as preservatives in feed for all animals and the use of ammonium and sodium formates as silage additives.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

ANALISIS KADAR PENGAWET BORAKS PADA BLENG DAN KERUPUK PULI YANG DIPRODUKSI OLEH BEBERAPA HOME INDUSTRI KABUPATEN MAGETAN [PDF]

open access: yes, 2007
Puli crisply is one of kind crisply which made of rice upon. Beside that, oftentimes the processing is enhanced by bleng. Bleng is phosphate salt condensation, in form of crystal, and yellowish chromatic, the content have many boron element and some ...
WIJAYANTI, RENI
core  

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