Results 71 to 80 of about 51,975 (267)

Preservation of Nitrosomonas [PDF]

Nature, 1957
IT is well known that the isolation of Nitrosomonas in pure culture is rather difficult; another problem is how the pure cultures can be successfully preserved. Nitrosomonas seems to be more frail than most other bacteria when in pure culture, and unfortunately the majority of strains isolated during past years have been lost.
openaire   +2 more sources

CURRENT STRATEGIES FOR THE USE OF ACTIVE PACKAGING IN FOOD PRODUCTS

Шәкәрім университетінің хабаршысы: Техника ғылымдар
Food quality and safety is one of the most important aspects of the food industry. One of the key factors to ensure food safety is packaging. Increasing number of food packaging materials is creating a demand for promoting products and brands that are ...
A. A. Zhanbolat, U. O. Tungyshbaeva
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Tolerability in Glaucoma Patients Switched from Preserved to Preservative-Free Prostaglandin-Timolol Combination: A Prospective Real-Life Study

Clinical Ophthalmology, 2022
Sonja Jandroković,1,2 Sania Vidas Pauk,1 Dina Lešin Gaćina,1 Ivan Skegro,1,2 Martina Tomić,3 Sanja Masnec,1,2 Tomislav Kuzman,1,2 Miro Kalauz1,2 1Department of Ophthalmology, University Clinical Hospital Center Zagreb, Zagreb ...
Jandroković S, Vidas Pauk S, Lešin Gaćina D, Skegro I, Tomić M, Masnec S, Kuzman T, Kalauz M   +7 more
doaj  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Scientific Opinion on the safety and efficacy of ammonium formate, calcium formate and sodium formate when used as a technological additive for all animal species

EFSA Journal, 2015
This opinion concerns the re‐authorisation of ammonium, calcium and sodium formates as preservatives in feed for all animals and the use of ammonium and sodium formates as silage additives.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Influence of Ethanol as a Preservative in Topical Formulation on the Dermal Penetration Efficacy of Active Compounds in Healthy and Barrier-Disrupted Skin

Pharmaceutics
(1) Background: Ethanol is a multifunctional excipient often used as a preservative in topical formulations. Due to its known ability to impair skin barrier function, this study investigated the effect of ethanol (EtOH) as a preservative in creams on the
Christian Raab, Tien Trung Do, Cornelia M. Keck   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source