Results 51 to 60 of about 66,976 (313)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Scientific Opinion on safety and efficacy of sodium benzoate, propionic acid and sodium propionate for pigs, poultry, bovines, sheep, goats, rabbits, horses

open access: yesEFSA Journal, 2012
The feed additive is a mixture of sodium benzoate 140 g/kg, propionic acid 370 g/kg and sodium propionate 110 g/kg and is intended to be used as a preservative for cereals high with a high moisture content.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Formulasi Tea Tree Oil sebagai Pengawet dalam Masker Gel Peel-Off Ekstrak Etanol Beras Merah (Oryza rufipogon Griff.)

open access: yesJPSCR: Journal of Pharmaceutical Science and Clinical Research
Bahan pengawet merupakan eksipien yang sangat dibutuhkan dalam sediaan cair seperti masker gel peel-off ekstrak etanol beras merah. Penggunaan paraben diyakini memiliki efek samping jangka panjang pada sistem endokrin dan reproduksi sehingga perlu ...
Eka Wulansari   +2 more
doaj   +1 more source

Scientific Opinion on the safety and efficacy of formaldehyde as a feed hygiene substance in feed for pigs and poultry [PDF]

open access: yesEFSA Journal, 2014
The additive formaldehyde is an aqueous solution of formaldehyde (34–38 % w/w by specification) and methanol (0.5–15.0 % v/v by specification), with a maximum concentration of formic acid of 0.05 %.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Challenges and opportunities related to the use of chitosan as food preservative

open access: yes, 2019
Chitosan has attracted a growing attention as a food preservative due to its versatility, nontoxicity, biodegradability and biocompatibility. This review aims to provide a critical appraisal of the limitations and opportunities of the use of chitosan as ...
Hu, Ziyi, Gänzle, Michael G.
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Safety and efficacy of a feed additive consisting on Ligilactobacillus animalis ATCC PTA‐6750 (formerly Lactobacillus animalis) for all animal species (Chr. Hansen A/S)

open access: yesEFSA Journal, 2021
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the additive consisting of Ligilactobacillus animalis (formerly known as ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +25 more
doaj   +1 more source

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