Results 91 to 100 of about 138,633 (304)

Circular 40 [PDF]

open access: yes, 1980
For cooperation and assistance in the work reported here, we gratefully acknowledge Dr. William Burgoyne, State of Alaska Division of Environmental Conservation and Mr. Delon Brown, USDA, Alaska Crop and Livestock Reporting Service.
Bleicher, David P.   +2 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Tolerability in Glaucoma Patients Switched from Preserved to Preservative-Free Prostaglandin-Timolol Combination: A Prospective Real-Life Study

open access: yesClinical Ophthalmology, 2022
Sonja Jandroković,1,2 Sania Vidas Pauk,1 Dina Lešin Gaćina,1 Ivan Skegro,1,2 Martina Tomić,3 Sanja Masnec,1,2 Tomislav Kuzman,1,2 Miro Kalauz1,2 1Department of Ophthalmology, University Clinical Hospital Center Zagreb, Zagreb ...
Jandroković S   +7 more
doaj  

Tannin resin-boron associations: Leaching and biological resistance [PDF]

open access: yes, 2012
The easy leaching of boron in wood preservation formulations has allowed to use this fungicide only for short term applications. The recently discovered adduct with flavonoids allows boron to resist longer periods of time within wood and consequently ...
Leménager, Nicolas   +5 more
core  

Preservationism in the Epistemology of Memory [PDF]

open access: yes, 2016
Preservationism states that memory preserves the justification of the beliefs it preserves. More precisely: if S formed a justified belief that p at t1 and retains in memory a belief that p until t2, then S's belief that p is prima facie justified via ...
Frise, Matthew
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Scientific Opinion on the safety and efficacy of ammonium formate, calcium formate and sodium formate when used as a technological additive for all animal species

open access: yesEFSA Journal, 2015
This opinion concerns the re‐authorisation of ammonium, calcium and sodium formates as preservatives in feed for all animals and the use of ammonium and sodium formates as silage additives.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Influence of Ethanol as a Preservative in Topical Formulation on the Dermal Penetration Efficacy of Active Compounds in Healthy and Barrier-Disrupted Skin

open access: yesPharmaceutics
(1) Background: Ethanol is a multifunctional excipient often used as a preservative in topical formulations. Due to its known ability to impair skin barrier function, this study investigated the effect of ethanol (EtOH) as a preservative in creams on the
Christian Raab   +2 more
doaj   +1 more source

Preservation Methods Differ in Fecal Microbiome Stability, Affecting Suitability for Field Studies. [PDF]

open access: yes, 2016
Immediate freezing at -20°C or below has been considered the gold standard for microbiome preservation, yet this approach is not feasible for many field studies, ranging from anthropology to wildlife conservation.
Amnon Amir   +7 more
core   +2 more sources

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