Results 101 to 110 of about 151,112 (335)
A tiny new species of Platypelis from the Marojejy National Park in northeastern Madagascar (Amphibia: Microhylidae) [PDF]
, 2012 We describe a tiny new frog species of the genus Platypelis (Anura: Microhylidae: Cophylinae) from Marojejy National Park, northeastern Madagascar. Platypelis ravus sp. nov.
Glaw, Frank +2 more
core +2 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Pharmaceutics(1) Background: Ethanol is a multifunctional excipient often used as a preservative in topical formulations. Due to its known ability to impair skin barrier function, this study investigated the effect of ethanol (EtOH) as a preservative in creams on the
Christian Raab +2 more
doaj +1 more source
, 1980 For cooperation and assistance in the work reported here, we gratefully acknowledge Dr. William Burgoyne, State of Alaska Division of Environmental Conservation and Mr. Delon Brown, USDA, Alaska Crop and Livestock Reporting Service.
Bleicher, David P. +2 more
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Investigation of the Influence of Antimicrobial Preparations on the Shelf Life of Broccoli Cabbage [PDF]
, 2018 Studies of the effect of antimicrobial agents on the conservation of broccoli cabbage have been conducted. The late hybrids of broccoli Ironman F1, Agassi F1, Beaumont F1, grown under the conditions of the Forest-Steppe of Ukraine were studied.
Bondarenko, V. (Veronika) +4 more
core +2 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Tannin resin-boron associations: Leaching and biological resistance [PDF]
, 2012 The easy leaching of boron in wood preservation formulations has allowed to use this fungicide only for short term applications. The recently discovered adduct with flavonoids allows boron to resist longer periods of time within wood and consequently ...
Leménager, Nicolas +5 more
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
First report on the termiticidal activity of extracts of Annona squamosa (Annonaceae) seeds and on its active constituent squamocins [PDF]
, 2012 Termites inflict severe damage on wood and impede usage of several forest species. The biological metabolites could potentially replace synthetic termiticidal products which are becoming more restricted to use.
Amusant, Nadine +4 more
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