Results 91 to 100 of about 12,773,604 (366)
Understanding Data Better with Bayesian and Global Statistical Methods [PDF]
in "Unsolved Problems in Astrophysics", Proceedings of Conference
in Honor of John Bahcall, J.P. Ostriker, ed. (Princeton: Princeton University
Press, 1996 [in press]), 1996 To understand their data better, astronomers need to use statistical tools that are more advanced than traditional ``freshman lab'' statistics. As an illustration, the problem of combining apparently incompatible measurements of a quantity is presented from both the traditional, and a more sophisticated Bayesian, perspective.
arxiv
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren +4 more
wiley +1 more source
New Microbes and New Infections, EarlyView., 2014 Abstract We describe a case of fungal keratitis due to Beauveria bassiana in a farmer with Fuchs' dystrophy, treated with amphotericin B. Surgery with penetrating keratoplasty was necessary to resolve the lesions. Susceptibility testing and molecular sequencing permitted the identification and treatment of this rare aetiological agent of invasive ...
M. Ligozzi +8 more
wiley +1 more source
What is non-formal learning (and how do we know it when we see it)? A pilot study report
Discover EducationIn this paper we consider the issue of formality in learning. Both formal and informal learning appear to be well-defined in educational discourse, in contrast with non-formal learning which is less clearly articulated.
Martin Johnson, Dominika Majewska
doaj +1 more source
Uniquely Pressable Graphs: Characterization, Enumeration, and Recognition [PDF]
arXiv, 2017 We consider "pressing sequences", a certain kind of transformation of graphs with loops into empty graphs, motivated by an application in phylogenetics. In particular, we address the question of when a graph has precisely one such pressing sequence, thus answering an question from Cooper and Davis (2015).
arxiv
Molecular Oncology, EarlyView.The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh +6 more
wiley +1 more source
Reply to C. Tsallis' Comment on our "Nonadditive Entropies Yield Probability Distributions with Biases not Warranted by the Data" [PDF]
arXiv, 2015 We reply to Tsallis' Comment on our "Nonadditive Entropies Yield Probability Distributions with Biases not Warranted by the Data" which first appeared in PRL.
arxiv
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Civil society organizations at the gates? A gatekeeping study of news making efforts by NGOs and government institutions [PDF]
, 2013 This article applies a combination of an input-output content analysis and in-depth interviews with NGO communication professionals to determine whether the growing incorporation of press releases in editorial print content could be a new public forum ...
Joye, Stijn, Van Leuven, Sarah
core +2 more sources