Results 141 to 150 of about 9,465,006 (361)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Is nurse-measured blood pressure a valid substitute for ambulatory blood pressure monitoring?
, 2000 BACKGROUND: Because ambulatory blood pressure monitoring (ABPM) is not available everywhere, the objective of the study was to determine whether nurse-measured blood pressure could be an acceptable substitute to ABPM.
Gerc, V. +3 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Exchange Market Pressure in Australia [PDF]
This paper measures the exchange market pressure (EMP) on the Australian dollar over the post-float period using the model-dependent approach proposed by Weymark (1995, 1998) and the model-independent approach developed by Eichengreen, Rose and Wyplosz ...
Shakila Jeisman
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Melting and sublimation of graphene and silicene
Physics of Complex SystemsThis study involves molecular dynamics simulations aimed at investigating the crystal structure collapse of graphene, graphite and silicene. It shows that in the case of graphene and graphite, crystal structure collapse is related to the sublimation of ...
Юрий Дмитриевич Фомин +2 more
doaj +1 more source
Cricoid Pressure: The Pressure is ON!
The Indian Anaesthetists' Forum, 2015 For many years Cricoid pressure (CP) has been a standard of care during induction of anaesthesia in emergency situations and where the patient is deemed at risk for aspiration of stomach contents (Rapid Sequence Induction or RSI). This review will examine the technique and its history; discuss the usual arguments presented as justification for ...
openaire +1 more source
Pore Water Pressure in Sand Bed under Oscillating Water Pressure
, 1984 In this paper the theoretical method to analyse the pore water pressures in the sand bed under the oscillating water pressure is developed. In the former researchs the validity of the theoretical treatment for the one-dimensional problem has been ...
Maeno, Shiro, Nago, Hiroshi
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source