Results 51 to 60 of about 8,297,853 (296)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Distribution of intraocular pressure in a Swedish population

open access: yesUpsala Journal of Medical Sciences, 2022
Background: Increased intraocular pressure (IOP) and pseudoexfoliation (PEX) are major risk factors for open-angle glaucoma (OAG), an age-related neurodegenerative disease of significant importance for public health. There are few studies on the distribution of IOP in populations where PEX is a common finding.
Maria Häkkinen, Curt Ekström
openaire   +4 more sources

Rock pressure distribution law of roadway based on displacement back analysis method

open access: yesMeikuang Anquan, 2023
Taking gob-side entry retaining in Sichuan Coal Group Xuyong No.1 mine as an engineering background, the displacement inverse analysis method is used to calibrate the physical and mechanical parameters test results of coal and rock, and the numerical ...
TANG Jianxin   +7 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Pressure Distribution in a Squeeze Film Spherical Bearing with Rough Surfaces Lubricated by an Ellis Fluid [PDF]

open access: yes, 2016
In this paper, the solution to a problem of pressure distribution in a curvilinear squeeze film spherical bearing is considered. The equations of motion of an Ellis pseudo-plastic fluid are presented.
Falicki, J.   +3 more
core   +1 more source

Numerical investigations on the sabots discard process of an APFSDS at different angles of attack

open access: yesThe Journal of Engineering, 2018
Sabot asymmetric discard after the projectile being launched from the muzzle at various angles of attack and 4Ma is investigated. This is implemented by the coupling computational fluid dynamics (CFD) and six degrees-of-freedom exterior ballistic code ...
Zhengui Huang   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Optimization Study of Gas Supply Pipeline Systems Based on Swarm Intelligence Optimization Algorithms

open access: yesApplied Sciences
With rapid urbanization and industrialization in China, existing gas supply networks urgently require renewal and optimization. This paper proposes a Gray Wolf Optimizer (GWO)-based method for reducing calculation errors and a Zebra Optimization ...
Li Dai, Chao Xu, Yiqun Liu, Liang Zeng
doaj   +1 more source

Premazi osetljivi na pritisak - nova mogućnost vizualizacije strujanja / Pressure sensitive paints: New possibility of flow visualization

open access: yesVojnotehnički Glasnik, 2006
U radu je opisan novi metod vizualizacije strujanja i merenje raspodele pritisaka po površini, baziran na premazima, odnosno bojama osetljivim na pritisak - PSP. Ovi premazi nalaze široku primenu u različitim oblastima nauke i industrije.
Slavica Ristić
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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