Results 61 to 70 of about 7,952,101 (296)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Air Knives: Going Beyond the Classical Midspan Pressure Distributions

Fluids
Air knives are extensively employed in many cold rolling or tin plate production lines for drying purposes. Generally, these systems are oversized, resulting in excessive energy consumption, a consequence of insufficient understanding of their ...
Celia Miguel-González, Aitor Vega-Valladares, Manuel García-Díaz, Alejandro Rodrígurez de Castro, José González Pérez, Bruno Pereiras   +5 more
doaj   +1 more source

Effect of Pressure Distribution on the Energy Dissipation of Lap Joints under Equal Pre-tension Force

Open Physics, 2019
In this paper, the energy dissipation in a bolted lap joint is studied using a continuum microslip model. Five contact pressure distributions compliant with the power law are considered, and all of them have equal pretension forces.
Sun Delin, Zhu Minggao
doaj   +1 more source

The Influence of applied pressure on the seated person and the prediction of early discomfort – protocol for a systematic review

International Journal of Occupational and Environment Safety, 2019
Sitting comfortably in a vehicle, office or at home, besides design characteristics, requires excellent physical support of the material to the exposed body segments.
Marko Cvetkovic, J. Duarte, Denise Soares, J. Santos Baptista   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Flow field through a gate valve installed in a circular pipe and loss coefficient

Nihon Kikai Gakkai ronbunshu, 2015
The loss coefficient and the flow fields downstream of the typical models of gate valves are investigated experimentally from the surface pressure and velocity distributions measured in the air-pipe flow at Reynolds number 4×104 and the various ...
Hidemi YAMADA, Yasuhiro NAKAHARA, Takahiro TSUCHIYA   +2 more
doaj   +1 more source

Static Characteristics of a Tilting Five-Pad Journal Bearing with an Asymmetric Geometry

Actuators, 2020
In this paper, static characteristics of a tilting five-pad rocker-backed journal bearing with an asymmetric geometry, i.e., different clearance for each pad, are investigated.
Phuoc Vinh Dang, Steven Chatterton, Paolo Pennacchi   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Effect of Soccer Foot Pressure on Pressure Distributions

Journal of Education and Training Studies, 2018
The aim of this research is to investigate the effect of playing soccer for a long time in for professional soccer players regarding sole pressure. Despite the increasing prevalence of new methods developed in the footpad pressure measurement in recent years, our knowledge about pressure distribution of the footplate is still insufficient, especially ...
KANATLI, ULUNAY, PEKEL, HACI AHMET, KAYA, METİN, AYDOS, LATİF, UZUN, AHMET   +4 more
openaire   +3 more sources