Results 71 to 80 of about 3,964,851 (289)

Flow Field Simulation for High Speed Train Gearbox

open access: yes机车电传动, 2017
Regarding the gearbox of a certain type high speed train as the research object, the simulation and analysis of the complex internal flow field during its normal operation was carried out. Three-dimensional model of the gearbox oil lubrication was built,
YANG Zhongkun   +3 more
doaj  

Magnetic-field-induced transition in BaVS3

open access: yes, 2007
The metal-insulator transition (MIT) of BaVS3 is suppressed under pressure and above the critical pressure of p~2GPa the metallic phase is stabilized. We present the results of detailed magnetoresistivity measurements carried out at pressures near the ...
G. Mihály   +8 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Pressure Field Over Europe and North Atlantic Favourable for The Occurrence of Clear and Cloudy Days in Poland

open access: yesMiscellanea Geographica: Regional Studies on Development, 2006
In this paper, results of research concerning circulation conditions favouring the occurrence of clear and cloudy days in Poland are presented. An analysis of the mean pressure field over North Atlantic and Europe on such days was performed, differences ...
Żmudzka Elwira
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Geosynchronous Magnetic Field Response to Solar Wind Dynamic Pressure [PDF]

open access: yesJournal of Astronomy and Space Sciences, 2011
The present study examines the morning-afternoon asymmetry of the geosynchronous magnetic field strength on the dayside (magnetic local time [MLT] = 06:00~18:00) using observations by the Geostationary Operational Environmental Satellites (GOES) over a
Jong-Sun Park   +4 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Effects of external magnetic field and hydrostatic pressure on magnetic and structural phase transitions in Pr0.6Sr0.4MnO3

open access: yes, 2018
We investigate the effect of hydrostatic pressure on temperature dependence of magnetization and also the influence of magnetic field on linear thermal expansion in polycrystalline Pr0.6Sr0.4MnO3, which is ferromagnetic at room temperature (TC = 305 K ...
Chanda, Amit, Mahendiran, R.
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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