Results 81 to 90 of about 3,986,628 (294)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Negative Pressures in QED Vacuum in an External Magnetic Field
, 2006 Our aim is to study the electron-positron vacuum pressures in presence of a strong magnetic field $B$. To that end, we obtain a general energy-momentum tensor, depending on external parameters, which in the zero temperature and zero density limit leads ...
Casimir H. B. G. +8 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Stress Field Distribution in Magnetoelastic Pressure Force Sensor
Communications, 2010 Modelling of the stress field distribution in a magnetoelastic sensor core is proposed. The components of stress field are carried out by a numerical solution of boundary-value problem for stress field.
Iveta Tomcikova +2 more
doaj +1 more source
Circumferential pressure distributions in a model labyrinth seal [PDF]
, 1982 A research program to isolate and study leakage flow through labyrinth glands was initiated. Circumferential pressure distributions were measured in the labyrinth glands with geometry appropriate to the high pressure labyrinths in large steam turbines ...
Brown, R. D., Leong, Y. M. M. S.
core +1 more source
, 2011 The effect of magnetic field on the nonlinear growth rate of Rayleigh-Taylor instability induced two fluid interfacial structures has been investigated.
Gupta, M. R. +3 more
core +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Unsteady Pressure Field Investigation of an Axial Fan—Blade Unsteady Pressure Field Measurement
International Journal of Rotating Machinery, 2002 Xu C., Amano R. S.
doaj +1 more source