Results 111 to 120 of about 373,369 (294)

Formation of adhesion domains in stressed and confined membranes

, 2015
The adhesion bonds connecting a lipid bilayer to an underlying surface may undergo a condensation transition resulting from an interplay between a short range attractive potential between them, and a long range fluctuation-induced potential of mean force.
Dharan, Nadiv, Farago, Oded
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Smart materials application on high performance sailing yachts for energy harvesting [PDF]

, 2013
Piezoelectric patches are bounded on a keel bulb in order to harvest vibration energy by converting electrical output. Unsteady computational fluid dynamics method is also used to find the structural boundary condition such as the hydrodynamic pressure ...
Khorasanchi, Mahdi, Mylonas, Dimitrios, Turkmen, Serkan   +2 more
core  

Spin Fluctuation-Induced Superconductivity in Organic Compounds

, 1998
Spin fluctuation-induced superconductivity in two-dimensional organic compounds such as \kappa-(ET)_2-X is investigated by using a simplified dimer Hubbard model with right-angled isosceles triangular lattice (transfer matrices -\tau, -\tau^\prime).
Anderson P. W., Bickers N. E., Dahm T., Kanoda K., Kawamoto A., Kino H., Koikegami S., Kontani H., Langer M., Mayaffre H., Miyake K., Monthoux P., Monthoux P., Moriya T., Nakamura S., Oshima K., Pao C.-H., Saito G., Schirber J. E., Sushko Yu. V., Takimoto T.   +20 more
core   +1 more source

Fluctuation [PDF]

Circulation, 2012
Effective drug treatment of hypertension for the prevention of fatal and nonfatal cardiovascular disease passed its 50th anniversary 2 years ago.1 Until recently, the most consistent observation among trials had been that stroke risk was directly related to the fall in blood pressure on treatment.2 Older trials established the value of antihypertensive
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

3D Structures on Relativistic Jets

, 1999
The properties of wave-like helically twisted normal mode structures on steady relativistic jets are summarized. Wave speeds are a function of the wavelength and less than the jet speed.
Biretta, Biretta, Birkinshaw, Gill, Hardee, Hardee, Hardee, Hardee, Junor, Keppens, Owen, Payne, Philip E. Hardee, Reid, Rosen, Xu, Zensus   +16 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source