Results 51 to 60 of about 625,652 (304)

Understanding the hospital sharps injury reporting pathway [PDF]

, 2015
INTRODUCTION: Patient-care workers are frequently exposed to sharps injuries, which can involve the risk of serious illness. Underreporting of these injuries can compromise prevention efforts.
Aiken, Alvarado-Ramy, Amick, Azaroff, Boden, Boden, Bureau of Labor Statistics USDoL, Cutter, d'Errico, Davis, Doebbeling, Elder, Galizzi, Hopcia, Karasek, Kim, Laramie, Menzel, Moore, Osborne, Panlilio, Pransky, Probst, Probst, Probst, Probst, Quinn, Rodríguez Acosta, Rosenman, Siddharthan, Sorensen, Tandberg, Voide, Wuellner   +33 more
core   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Investigation of the Relationship between Pressure and Injury by Impacting Ex Vivo Perfused Spleens [PDF]

, 2014
Motor vehicle crashes (MVCs) can be fatal and may induce permanent disability to the individuals involved. MVCs may result in injury to different body regions, but in particular, the abdomen is a site of life-threatening injuries due to housing vital ...
Ryu, Yeonsu
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

We See Ourselves as a Part of the Healthcare Team: Involving Patients and Their Caregivers in the Prevention of Hospital-acquired Pressure Injuries [PDF]

Journal of Client-centered Nursing Care
Pressure injuries are the most common adverse effect of shear and pressure in the hospital. Pressure ulcers usually occur on a bony prominence in hospitals and pose a risk to patient safety. These injuries indicate poor health care quality.
Nader Aghakhani, Rahim Nejadrahim, Pedram Abolfathpour   +2 more
doaj  

Strategies to preventing pressure injuries among intensive care unit patients mechanically ventilated in prone position: a systematic review and a Delphi study

Frontiers in Medicine, 2023
BackgroundAlthough the incidence of pressure injury in the prone position is high for the mechanically ventilated patients in the intensive care unit, evidence-based strategies are still lacking.ProposeTo conduct a systematic review of current evidence ...
Zonghua Wang, Jiangshan Fan, Ling Chen, Langlang Xie, Lingfang Huang, Yang Ruan, Xia Xu, Zeping Liang   +7 more
doaj   +1 more source

Attenuation of Focal Cerebral Ischemic Injury Following Post Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat [PDF]

Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from ...
دهقان, غلامعباس, پناهپور, حمداله   +1 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

On the Origin of Intraoperative Pressure Injury: An Angiosomal Theory of Pressure Injury Formation [PDF]

Advances in Wound Care, 2019
We review a case of a 22-year-old healthy man who underwent a 5-h maxillofacial surgery while continuously supine with foam pads placed prophylactically over elevated heels. Immediately after surgery, Stage 1 pressure injuries appeared on the left lateral heel and right lateral ankle, despite the absence of local pressure to these areas.
Caroline E. Fife, Efthymios Gkotsoulias
openaire   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source