Results 91 to 100 of about 4,048,426 (298)

Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (HARP-2) trial : study protocol for a randomized controlled trial [PDF]

, 2012
Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure.
O'Kane, Cecilia M., O’Kane, Cecilia M., Laffey, John G, Cross, Mark, John G Laffey, McAuley, Daniel F; id_orcid, McNally, Christine, Michael Stevenson, Perkins, Gavin D., Crealey, Grainne, Laffey, John G., Daniel F McAuley, Murphy, Lynn, HASH(0x55a67ff73468), Stevenson, Michael, Cross, L. J. Mark, Grainne Crealey, Cecilia M O’Kane, McAuley, Daniel F., Mark Cross, null null, Gavin D Perkins, Perkins, Gavin D, Christine McNally, Lynn Murphy, O'Kane, Cecilia M, Cross Mark, Stevenson Michael, Murphy Lynn, McNally Christine, Crealey Grainne, Laffey John G, O’Kane Cecilia M, McAuley Daniel F, Perkins Gavin D   +34 more
core   +2 more sources

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Editorial: Soft Tissue Biomechanics in Wound Healing and Prevention

Frontiers in Bioengineering and Biotechnology, 2022
Yih-Kuen Jan, Matthew J. Major, Matthew J. Major, Fang Pu, Sharon Eve Sonenblum   +4 more
doaj   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Surgical management of stage 3 and 4 pressure injuries in trauma patients using ovine forestomach matrix grafts: a prospective case series

Frontiers in Surgery
IntroductionStage 3 and 4 pressure injuries (PIs) pose significant challenges in trauma patients. Surgical management aims to support improvements in tissue vitality and often relies on debridement and negative pressure wound therapy.
Sophia M. Trinh, Kaitlyn Andre, Ada I. Özcan, Dhanushka S. Vitharana, Paige E. Deville, Joseph W. Mason, John P. Hunt, Alan B. Marr, Patrick P. Greiffenstein, Lance E. Stuke, Alison A. Smith   +10 more
doaj   +1 more source

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

Arthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada, Marcos Rafael N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source

Sex and age differences in mechanical, thermal and wetness perception across skin sites at risk of pressure ulcers: A quantitative sensory testing study

Experimental Physiology
Pressure ulcers can be common in the elderly, and loss of sensation can play a fundamental role in the development of these injuries. The aim of this study was to assess the effects of age and sex on non‐noxious thermal and wetness perception (via ...
Miriam Martini, Arianna Ortis, Davide Filingeri, Peter R. Worsley, Evelin Makuc, Manuela Deodato, Luigi Murena, Paolo Manganotti, Alex Buoite Stella   +8 more
doaj   +1 more source

Design of Deep Learning-Based Pressure Injury Stage Classification Device

Jurnal Rekayasa Elektrika
Pressure injury or pressure ulcers could occur due to continuous pressure on the bony prominence of the skin and tissue. Geriatric patients, especially those with limited mobility and several comorbidities, are more susceptible to pressure injury.
Wahmisari Priharti, Husneni Mukhtar, I Made Prastha Giriwara, I Made Andi Majesta, Wayan Abin Bena Bimantara   +4 more
doaj   +1 more source