Early cerebral perfusion pressure augmentation with phenylephrine after traumatic brain injury may be neuroprotective in a pediatric swine model* [PDF]
, 2012 Objective: Cerebral perfusion pressureage, and current guidelines recommend maintaining cerebral perfusion pressure between 40 mm Hg–60 mm Hg. Although adult traumatic brain injury studies have observed an increased risk of complications associated with ...
Adelson +31 more
core +2 more sources
Guanylyl cyclase activation reverses resistive breathing–induced lung injury and inflammation [PDF]
, 2015 Inspiratory resistive breathing (RB), encountered in obstructive lung diseases, induces lung injury. The soluble guanylyl cyclase (sGC)/cyclic guanosine monophosphate (cGMP) pathway is down-regulated in chronic and acute animal models of RB, such as ...
Brouckaert, Peter +15 more
core +2 more sources
Informatics, 2017 The selection of appropriate wound products for the treatment of pressure injuries is paramount in promoting wound healing. However, nurses find it difficult to decide on the most optimal wound product(s) due to limited live experiences in managing ...
Peck Chui Betty Khong +2 more
doaj +1 more source
Pressure injury in Australian public hospitals: a cost-of-illness study [PDF]
, 2015 Objective: Pressure injuries (PI) are largely preventable and can be viewed as an adverse outcome of a healthcare admission, yet they affect millions of people and consume billions of dollars in healthcare spending.
Allman +34 more
core +1 more source
Trauma Early Mortality Prediction Tool (TEMPT) for assessing 28-day mortality. [PDF]
, 2018 Background:Prior mortality prediction models have incorporated severity of anatomic injury quantified by Abbreviated Injury Severity Score (AIS). Using a prospective cohort, a new score independent of AIS was developed using clinical and laboratory ...
Callcut, Rachael A +3 more
core +1 more source
Cerebral autoregulation, brain injury, and the transitioning premature infant [PDF]
, 2017 Improvements in clinical management of the preterm infant have reduced the rates of the two most common forms of brain injury, such as severe intraventricular hemorrhage and white matter injury, both of which are contributory factors in the development ...
Mathur, Amit M, Vesoulis, Zachary A
core +3 more sources
Mitigating perioperative pressure injuries in microsurgical breast reconstruction
Frontiers in SurgeryPressure injuries (PI) that develop in the operating room (OR) account for just under half of all hospital acquired pressure injuries (HAPI) and contribute significantly to the high cost and patient morbidity of HAPI.
Amanda Fazzalari +3 more
doaj +1 more source
, 2008 Identifying patients at risk of traumatic brain injury (TBI) is important because research suggests prophylactic treatments to reduce risk of long-term sequelae.
Alexander MP +29 more
core +1 more source
Prevention of pressure injury in the operating room: Heels operating room pressure injury trial [PDF]
International Wound Journal, 2020 AbstractThe objective was to evaluate the efficacy of multi‐layered silicone foam (intervention) compared with transparent polyurethane film (control) in preventing heel pressure injuries caused by surgical positioning of individuals undergoing elective surgery. It was designed an intra‐patient, open, parallel, randomised controlled trial was conducted
Dresch Eberhardt, Thaís +7 more
openaire +4 more sources
Circulating microRNAs Reveal Time Course of Organ Injury in a Porcine Model of Acetaminophen-Induced Acute Liver Failure [PDF]
, 2015 Acute liver failure is a rare but catastrophic condition which can progress rapidly to multi-organ failure. Studies investigating the onset of individual organ injury such as the liver, kidneys and brain during the evolution of acute liver failure, are ...
A O'Riordan +60 more
core +5 more sources