Results 91 to 100 of about 218,831 (310)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Pressure mapping of medical compression bandages used for venous leg ulcer treatment [PDF]

, 2010
Chronic leg ulcers affect 1% of the adult population in the developed countries. The majority of leg ulcers are due to venous disease. The impact of venous ulcers on the quality of life is significant, and it costs the NHS £300 − 600m annually.
Al Khaburi, Jawad Ameen Jawad
core  

Investigation of shock waves in explosive blasts using fibre optic pressure sensors

, 2005
The published version of this article may be accessed at the link below. Copyright @ IOP Publishing, 2006.We describe miniature all-optical pressure sensors, fabricated by wafer etching techniques, less than 1 mm(2) in overall cross-section with rise ...
Pichugin, AV, A Tyas, A Hindle, Tyas, A, Parkes, W., J D C Jones, Hindle, A., Jones, J. D C, Watson, S., Pichugin, A. V., MacPherson, W. N.; id_orcid, Dunare, C., Watson, S, W N MacPherson, Dunare, C, Stevenson, T, Jones, JDC, A V Pichugin, Stevenson, T., T Stevenson, Hindle, A, MacPherson, WN, C Dunare, Barton, J. S., Tyas, A., W Parkes, Parkes, W, S Watson, J S Barton, Barton, JS   +29 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Design, Fabrication, and Implementation of a Wireless, Passive Implantable Pressure Sensor Based on Magnetic Higher-Order Harmonic Fields

Biosensors, 2011
A passive and wireless sensor was developed for monitoring pressure in vivo. Structurally, the pressure sensor, referred to as the magneto-harmonic pressure sensor, is an airtight chamber sealed with an elastic pressure membrane.
Keat Ghee Ong, Brandon D. Pereles, Andrew J. DeRouin, Ee Lim Tan   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Design of Intelligent Pressure Sensor Based on PSO‑BP Temperature Compensation Algorithm

Nanjing Hangkong Hangtian Daxue Xuebao
Pressure is an important physical signal that characterizes the operating performance of aero-engine. A design based on PSO-BP temperature compensation algorithm for intelligent pressure sensor is proposed for the high-precision measurement requirement ...
ZHANG Lingfeng, DING Xiaoyu, PAN Muxuan
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Avaliação em médio prazo da pressão intra-saco após correção endovascular de aneurisma de aorta abdominal com o uso de sensor sem fio [PDF]

, 2010
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Ciências Médicas.Justificativa: O objetivo do tratamento endovascular do aneurisma de aorta abdominal é a exclusão do saco ...
Lain, Vinícius Victorazzi
core  

Fabrication of a sensitive pressure sensor using carbon nanotube micro-yarns

, 2017
Developing flexible pressure sensors is of high interest in soft skin and tactile sensing applications. Here we demonstrate a simple approach to fabricating a sensitive resistive pressure sensor using carbon nanotube (CNT) micro-yarns as a pressure ...
Nguyen, Nam-Trung, Fastier-Wooller, Jarred, Phan, Hoang Phuong, Dao, Dzung, Jarred Fastier-Wooller, Canh-Dung Tran, Dinh, Toan, Nam-Trung Nguyen, Nguyen, Tuan-Khoa, Nguyen Tuan, Khoa, Tuan-Khoa Nguyen, Dao, Dzung Viet, Tran, Canh-Dung, Dzung Viet Dao, Hoang-Phuong Phan, Phan, Hoang-Phuong, Toan Dinh   +16 more
core   +1 more source