Results 101 to 110 of about 7,240,574 (352)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Exploitation of a pH-sensitive hydrogel for CO2 detection [PDF]
, 2003 In this paper is described how hydrogel is exploited as sensor material for the \ud detection of carbon dioxide (CO2). A pH-sensitive hydrogel disc, which swells and deswells in response to pH changes, was clamped between a pressure sensor membrane and a
Berg, A. van den +3 more
core +1 more source
Miniature photonic-crystal hydrophone optimized for ocean acoustics
, 2010 This work reports on an optical hydrophone that is insensitive to hydrostatic pressure, yet capable of measuring acoustic pressures as low as the background noise in the ocean in a frequency range of 1 Hz to 100 kHz.
Gordon S. Kino +7 more
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Experimental method for determination of the pressure distribution in granular solids
Research in Agricultural Engineering, 2003 This paper presents two methods of determination of pressure distribution in rape seeds. The study utilized hydraulic pressure sensors with active rubber face and stress state transducer with six duralumin face sensors.
R. Rusinek
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Validation of the Aquanex system to assess in-water forces during aquatic exercise
MotricidadeThe aim of this study was to perform a validation of the Aquanex system to assess in-water forces during aquatic exercise. One sensor (Type A) that composes the differential pressure system (Aquanex v.4.1, STR, USA) was placed inside a wind tunnel ...
Catarina Santos +5 more
doaj +1 more source
Proceedings, 2017 This paper presents a high sensitive micro-sensor designed for pressure measurements in a wide range around atmospheric pressure, for application in aerodynamics.
Cécile Ghouila-Houri +9 more
doaj +1 more source
Effects of high temperature and pressure on silica optical fibre sensors
, 1998 We report on the effects of liquids at high temperature and pressure on silica optical fibres, sensors and gratings. We propose that the diffusion of molecules into the silica and the resultant expansion of the network are responsible for observed fibre ...
Clowes, J.R. +3 more
core +1 more source