Results 121 to 130 of about 7,240,574 (352)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Development of optical diaphragm deflection sensors [PDF]

open access: yes
The objective of this project was to develop high-temperature pressure sensors using non-metallic components and optical sensing methods. The sensors are to operate over a temperature range from room temperature approx.
Bailey, R. T.   +4 more
core   +1 more source

Pioneer 10 Jupiter atmospheric definition results: A summary [PDF]

open access: yes, 1974
The various entry probes for measuring outer planetary atmospheric compositions are discussed. Considered are chemical components and physical accumulation processes observable by spectroscopic studies, as well as pressure gauges, temperature gauges ...
Kliore, A., Wolfe, J.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Long Period Fiber Grating Inscribed in Hollow-Core Photonic Bandgap Fiber for Gas Pressure Sensing

open access: yesIEEE Photonics Journal, 2017
In this paper, we have proposed and experimentally prepared an improved gas pressure sensing device. It is mainly constructed by a short hollow silica tube segment and a CO2-laser-induced long period grating in hollow-core photonic bandgap fiber (HC-PBF).
Jian Tang   +12 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

First principles modeling of pure black phosphorus devices under pressure

open access: yesBeilstein Journal of Nanotechnology, 2019
Black phosphorus (BP) has a pressure-dependent bandgap width and shows the potential for applications as a low-dimensional pressure sensor. We built two kinds of pure BP devices with zigzag or armchair conformation, and explored their pressure-dependent ...
Ximing Rong   +5 more
doaj   +1 more source

Systems and methods for measuring component matching [PDF]

open access: yes, 2006
Systems and methods for measuring a contour match between adjacent components are disclosed. In one embodiment, at least two pressure sensors are located between adjacent components.
Courter, Kelly J., Slenk, Joel E.
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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