Results 101 to 110 of about 14,747 (270)

Mesophotic ecosystems : distribution, impacts and conservation in the South Atlantic

, 2021
Unidad de excelencia María de Maeztu MdM-2015-0552Aim: this study reviews recent research on the South Atlantic Mesophotic ecosystems (MEs) and the pressures threatening them, and offers suggestions for their management and conservation.
Soares, Marcelo de Oliveira, Carneiro, Pedro Bastos de Macêdo, Tavares, Tallita Cruz Lopes   +2 more
core  

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Assessing the impacts of nonindigenous marine macroalgae: an update of current knowledge

, 2015
Nonindigenous marine species continue to be one of the foremost threats to marine biodiversity. As an update to a 2007 review of the impacts of introduced macroalgae, we assessed 142 additional publications to describe species’ impacts as well as to ...
Campbell, M.L., Davidson, Alisha D., Hewitt, C.L., Schaffelke, Britta, Schaffelke, B., Davidson, A.D., Hewitt, Chad L., Campbell, Marnie L.   +7 more
core   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Economic Evaluation and Biodiversity Conservation of Animal Genetic Resources [PDF]

Rapidly declining biodiversity has made international and national policies focus on the question of how best to protect genetic resources. Loss of biodiversity does not only concern wildlife, but equally affects agriculturally used species.
Bertaglia, Marco, Roosen, Jutta, Fadlaoui, Aziz   +2 more
core  

Conservation management of rivers and wetlands under climate change - a synthesis

, 2011
Dams, diversion of water, invasive species, overharvesting and pollution are degrading rivers and wetlands. Climate change may exacerbate impacts of these threats through predicted reductions in rainfall and increased temperature, decreasing flow and ...
Richard T. Kingsford
core   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

Anthropogenic Impacts Allowed for the Invasion of Understory Species, Affecting the Sustainability of Management Practices in Southern Patagonia

Land
Forest management aims to preserve integrity and ecosystem resilience. Conservation and species invasion patterns must be determined in managed landscapes. The objectives of this study were to identify proxies that allowed plant species invasion (natives
Yamina Micaela Rosas, Pablo Luis Peri, Juan Manuel Cellini, María V. Lencinas, Sebastian Kepfer Rojas, Inger Kappel Schmidt, Sebastián Pechar, Marcelo Daniel Barrera, Guillermo J. Martínez Pastur   +8 more
doaj   +1 more source

Evaluating the fishery and ecological consequences of the proposed North Sea multi-annual plan.

PLoS ONE, 2018
The possible impacts of the European Commission's proposed North Sea Multi-Annual Plan are evaluated in terms of its likely outcomes to achieve management objectives for fishing pressure, species' biomass, fishery yield, the landed value of key species ...
Steven Mackinson, Mark Platts, Clement Garcia, Christopher Lynam   +3 more
doaj   +1 more source