Results 111 to 120 of about 174,900 (265)

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +13 more
wiley   +1 more source

Selection of Marine Conservation Zones

, 2013
Marine Conservation Zones may contribute to the protection and recovery of the marine environment. This POSTnote examines the process and approach used to select and designate zones, and difficulties in identifying and managing suitable ...
Brown, Alastair, Wentworth, Jonathan
core  

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Optimal Grazing Exclusion Duration to Enhance Soil Carbon Sequestration in Degraded Grasslands

Advanced Science, EarlyView.
Across China, grazing exclusion reaches the national mean soil organic carbon recovery benchmark sooner in high‐MAP regions (> 500 mm), but recovery is much slower where MAP < 300 mm. Scaling this strategy to 70% of China's degraded grasslands would sequester about 1.52 Pg of soil carbon over 10 years—roughly 17% of annual global fossil‐fuel emissions.
Bin Zhang, Chongzhi Sun, Dongmei Xue, Paul Christiaan Struik, Tongrui Zhang, Jiayue Liu, Tingting Xing, Ziyang Liu, Shiming Tang, Ke Jin   +9 more
wiley   +1 more source

Targeting fin whale conservation in the North-Western Mediterranean Sea: insights on movements and behaviour from biologging and habitat modelling

Royal Society Open Science
Biologging and habitat modelling are key tools supporting the development of conservation measures and mitigating the effects of anthropogenic pressures on marine species.
Viola Panigada, Thomas W. Bodey, Ari Friedlaender, Jean-Noël Druon, Luis A. Huckstädt, Nino Pierantonio, Eduard Degollada, Beatriu Tort, Simone Panigada   +8 more
doaj   +1 more source

Tourists' perceptions of environmental impacts of tourism development on water resources in the Okavango Delta, Botswana. [PDF]

African Journal of Hospitality, Tourism and Leisure, 2017
The Okavango Delta is a unique inland water system supporting tourism development in Botswana. While the ecological integrity of the wetland remains intact, there are signs that it is being slowly eroded by increasing anthropogenic pressures like tourism
Owen Musora, Professor Joseph. E Mbaiwa , Dr Mike Murray-Hudson   +2 more
doaj  

An investigation into the concept of and factors leading to impact creep and its management [PDF]

, 2006
This study defines and explores the nature of impact creep within the context of two contrasting case studies. The methods applied in undertaking this study consisted of a literature review and development and distribution of questionnaires to visitors ...
Newsome, D., Smith, A.J.
core   +1 more source

Transdermal Delivery of an mRNA‐Liposome Vaccine via Dissolving Microneedle to Preserve Vaccine Activity and Enhance Immune Activation

Advanced Science, EarlyView.
An mRNA‐liposome vaccine via dissolving microneedles (ML‐DMN) enables efficient skin‐targeted delivery while preserving mRNA integrity and allowing sustained antigen expression. Unlike intramuscular (IM) injection, ML‐DMN engages skin‐resident immune cells, activates antigen‐presenting cells (APCs), and induces strong T cell and cytokine responses at ...
Jeehye Nam, JiWon Ahn, Jiwoo Shin, Nahong Lee, Youjin Lee, Sung min Cho, Paul Kim, Geonwoo Kang, Sang‐Jun Ha, Hyungil Jung   +9 more
wiley   +1 more source

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

Advanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li, Zhongshao Chen, Qianqian Gao, Yuehan Gao, Ning Yang   +4 more
wiley   +1 more source

Wild Boar Management and Environmental Degradation: A Matter of Ecophysiology—The Italian Case

Conservation
Despite its global distribution, the impacts of wild pigs on the environment are poorly understood. However, wild boar (Sus scrofa) is recognized as a pest species, causes extensive damage to agriculture, biodiversity, and forests, and contributes to ...
Andrea Mazzatenta
doaj   +1 more source