Results 111 to 120 of about 14,747 (270)

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Targeted FSC certification to increase conservation impact in the Congo Basin

Discover Forests
The forests of the Congo Basin are globally significant for biodiversity, climate regulation, and ecological integrity but face increasing pressures from industrial logging and illegal hunting.
Joeri A. Zwerts, Lois M. Oudejans, Mats Kruize, Koen W. S. Norbart, Fieke A. E. de Zwart, Jaap van der Waarde   +5 more
doaj   +1 more source

Missing the trees for the wood : why we are failing to see success in pro-poor conservation

, 2014
Date of Acceptance: 18/10/2013Pro-poor conservation strategies are touted as a panacea for achieving biodiversity conservation and poverty reduction, yet there remains limited evidence for success in achieving these dual objectives.
Cresswell, W., Pettorelli, N., Fazey, I. R. A., Davies, Tamara Ellen, Fazey, I.R.A., Cresswell, Will, Davies, T. E.   +6 more
core   +1 more source

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

Advanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao, Xin Wang, Jing Zhang, Ryan McQuinn, Je Min Lee, Itay Gonda, Ari Feder, Yimin Xu, Baike Wang, Qinghui Yu, Denise M. Tieman, Sanwen Huang, Harry Klee, James J. Giovannoni, Zhangjun Fei   +14 more
wiley   +1 more source

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

Advanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen, Wenliang Zhou, Lan Qiu, Han Lai, Mingpan Huang, Qian Li, Wen Yu, Pei‐Yuan Qian, Fuwen Wei   +8 more
wiley   +1 more source

Conservation Effectiveness and Spatial Drivers of Qianjiangyuan National Park: Causal Evidence from a Quasi-Experimental Framework

Land
National parks are widely recognized as a key spatial conservation strategy for simultaneously safeguarding biodiversity and sustaining ecosystem services, yet comprehensive and causally robust evaluation frameworks are still needed to accurately assess ...
Chuqi Wang, Yinglin Wang, Jiwen Lu, Liang Li   +3 more
doaj   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source

Wildlife persists in the Midlands Black Rhino Conservancy, Zimbabwe, but requires an emergency conservation plan

Geocarto International
The persistence of wildlife in the Midlands Black Rhino Conservancy (MBRC), Zimbabwe, highlights both species resilience and landscape value, yet escalating anthropogenic pressures demand urgent conservation action.
Nobert Tafadzwa Mukomberanwa, Briliant Makuwe Chibura, Honest Komborero Madamombe, Last Keche, Trevor Muchenjekwa, Diarson Ishmael Tsuro, Takudzwa Praisegod Murwadzi, Blessings Moyo, Munyaradzi Kadzere, Kelvin Charles Muredzi, Tadiwanashe Blessed Gwara, Amon Diwa, Melody Mutasa, Triumph Mugove Mukume, Nichol Mudzimiri, Mutsawashe Tadiwanashe Muzari, Osley Mudzanirwa, Wesley Tanatswa Mandonye, Akasha Alice Alison, Innocent Maradza, Ellen Boys, Nyasha Chelsea Madanhe, Brian Chinyanga, Tafadzwa Nyamahumba, Brendon Mharakurwa, Mitchell Chido Mugaviri, Active Farai Moses Nyamadzawo, Tinotenda Nyasha Mukinya, Dexter Farai Chigumira, Sarah Mudiwa Chikowero, Trevor Tinashe Chipfu, Mercy Joyline Mbarami, Michael Gwenzi, Florence Guchu, Kudakwashe Manyika, Mitchell Tendesai Zimunya, Munashe Manyika, Thembeka Sopuka, Andrew Takunda Bangwayo, Charlotte Tadiwa Taruvinga, Zvikomborero Samuel Mboto, Tsitsi Tamia Muchepa, Makanaka Muradzi, Isheanopa Pasco Gatsi, Courtney Mapuranga, Munyaradzi Chirova, Olinda Samantha Bisenti, Archiford Takaindisa, Wellington Muradzikwa, Fidelis Duncan Dzambo, Maxwell Parirewa, Taurai Allan Taru, Jeremiah Thabeti, Delight Panashe Mandiyanike, Takudzwa Chirambasadza   +54 more
doaj   +1 more source

Hierarchization of species and prioritization of conservation actions: towards a conservation strategy for flora, from biogeographical to regional level

, 2018
The Maritime and Ligurian Alps, located at the interface between the Alps Mountains and the Mediterranean region, constitute one of the regional biodiversity hotspots of the Mediterranean basin.
DIADEMA K., MÉDAIL F., MINUTO L., CASAZZA G., NOBLE V., FORT N., MARIOTTI M., LE BERRE M., ABDULHAK S., PIRES M.   +9 more
core  

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +13 more
wiley   +1 more source