Results 121 to 130 of about 174,900 (265)

A Modular and Programmable Cas13d Platform for RNA Single Nucleotide Variant Detection

Advanced Science, EarlyView.
A scenario‐guided Cas13d platform enables configurable single nucleotide variant ribonucleic acid diagnostics through rule‐based guide design and ribonucleic acid binding domain engineering, supporting amplification‐free ultrasensitive detection and amplification‐coupled robust detection for accurate mutation classification in clinical tumor specimens.
Zeyu Wang, Jiahao Li, Zhuying Yue, Beixuan He, Wenhua Zhang, Zhen Fang, Qing Xia, Yingbin Liu, Yanjing Li   +8 more
wiley   +1 more source

Mitochondrial Enzymes Mimetic Ultrasmall Palladium Nanozymes Prevent Senescence and Neurodegeneration Through Metabolic Reprogramming

Advanced Science, EarlyView.
Simply constructed polyvinylpyrrolidone (PVP) modified palladium nanoparticles (PdP NPs) as cytochrome c oxidase (CcO) and superoxide dismutase (SOD) mimic are promising multifunctional nanoreactors to boost mitochondrial respiration chain function and refine homeostasis via regulation of mitochondrial dynamics and proteostasis sensor UPRmt, which ...
Wenshu Cong, Haiming Jing, Zinan Li, Wenjing Zhang, Nan Zhang, Yingqiu Xie, Shan Gao, Yuanyu Huang, Junyu Ning   +8 more
wiley   +1 more source

Bioinspired Hierarchical Architecture with Water Transport Channels for Strong Adhesion at the Sweating Interface

Advanced Science, EarlyView.
To address adhesion failure in sweaty epidermal electronics, this study proposes a cross‐species, multi‐scale biomimetic interface. By modeling staged wet adhesion, it integrates self‐regulating liquid bridges with directional drainage. This design ensures stable, high‐performance flexible sensing in complex physiological environments, offering a ...
Jieliang Zhao, Yu Xiang, Heng Wang, Huiqing Xu, Zhong Liu, Lulu Liang, Fengwen Jiang, Xuemei Chen, Wenzhong Wang, Chenqing Liu, Guodong Liu, Shaoze Yan, Xu Hou   +12 more
wiley   +1 more source

Ocean governance: the New Zealand dimension [PDF]

  The Oceans Governance project was funded by the Emerging Issues Programme, overseen by the Institute of Policy Studies at Victoria University of Wellington. Its primary goal is to provide interested members of the public and policymakers with a
Michael Vincent McGinnis
core  

Anthropic pressures on Nature 2000 Sites: recommendations and monitoring criteria for the pollution emergency response activities within the Orbetello lagoon [PDF]

, 2007
L’elevato valore naturalistico e socioeconomico di un Sito Natura 2000 richiede che tutte le attività antropiche che si svolgono al suo interno (es.
Ausili, A., Barbara, W., Cappucci, S., De Propris, L., Gabellini, M., Giovanardi, F., Girardi, R., Mumelter, E., Onorati, F., Russo, S., Tornato, A., Trama, V., Trinchera, G.   +12 more
core   +1 more source

Introgressed Variation in TaMYB7‐A1 Drives Graded Dormancy and Climate‐Adaptive Pre‐Harvest Sprouting Resistance in Wheat

Advanced Science, EarlyView.
TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang, Dongzhi Wang, Yafei Guo, Qi Zheng, Min Zhang, James Simmonds, Jian Hou, Xuemei Liu, Xuelei Lin, Xiaomin Bie, Xiansheng Zhang, Xiaohui Li, Yuan Chen, Xueyong Zhang, Cristobal Uauy, Fei Lu, Chengcai Chu, Zhixi Tian, Jun Xiao   +18 more
wiley   +1 more source

A belowground perspective on the nexus between biodiversity change, climate change, and human well‐being

Journal of Sustainable Agriculture and Environment
Soil is central to the complex interplay among biodiversity, climate, and society. This paper examines the interconnectedness of soil biodiversity, climate change, and societal impacts, emphasizing the urgent need for integrated solutions.
Nico Eisenhauer, Karin Frank, Alexandra Weigelt, Bartosz Bartkowski, Rémy Beugnon, Katja Liebal, Miguel Mahecha, Martin Quaas, Djamil Al‐Halbouni, Ana Bastos, Friedrich J. Bohn, Mariana Madruga deBrito, Joachim Denzler, Hannes Feilhauer, Rico Fischer, Immo Fritsche, Claudia Guimaraes‐Steinicke, Martin Hänsel, Daniel B. M. Haun, Hartmut Herrmann, Andreas Huth, Heike Kalesse‐Los, Michael Koetter, Nina Kolleck, Melanie Krause, Marlene Kretschmer, Pedro J. Leitão, Torsten Masson, Karin Mora, Birgit Müller, Jian Peng, Mira L. Pöhlker, Leonie Ratzke, Markus Reichstein, Solveig Richter, Nadja Rüger, Beatriz Sánchez‐Parra, Maha Shadaydeh, Sebastian Sippel, Ina Tegen, Daniela Thrän, Josefine Umlauft, Manfred Wendisch, Kevin Wolf, Christian Wirth, Hannes Zacher, Sönke Zaehle, Johannes Quaas   +47 more
doaj   +1 more source

Opportunities to responsible land-based investments in Central Africa [PDF]

, 2013
Large-scale land-based investments in Central Africa are not new, however, the years 2000s have seen a renewed interest in agriculture by foreign investors.
Feintrenie, Laurène
core  

Microstructure‐Resolved Modeling to Predicting and Regulating Lithium Plating‐Stripping Dynamics on Graphite Electrodes

Advanced Science, EarlyView.
ABSTRACT The lithium plating reaction in graphite electrodes acts as a root cause for the accelerated degradation and the internal short circuits in lithium‐ion batteries. Here, an electrochemical model based on multi‐scale microstructural images was established to identify lithium plating‐stripping processes, thereby supporting the predictive outcomes
Heng Huang, Yang Li, Xinyu Liu, Zhifu Zhou, Wei‐Tao Wu, Lei Wei, Chengzhi Hu, Linsong Gao, Yubai Li, Yongchen Song   +9 more
wiley   +1 more source

Efficient Screening of Organic Singlet Fission Molecules Using Graph Neural Networks

Advanced Science, EarlyView.
A high‐throughput screening framework based on graph neural networks (GNNs) and multi‐level validation facilitates the identification of singlet fission (SF) candidates. By efficiently predicting excitation energies across 20 million molecules, and integrating TDDFT calculations, synthetic accessibility assessments, and GW+BSE calculations, this ...
Li Fu, Longfei Lv, Fan Zhang, Si Zhou, Weiwei Gao, Jijun Zhao   +5 more
wiley   +1 more source