Results 91 to 100 of about 72,936 (296)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Showing Mercy Through a Presumption of Retribution [PDF]
From the Article This Essay proposes a path toward the systematic consideration of mercy in American sentencing. America does not have to choose between retributive blame on the one hand and nonjudgmental mercy on the other.
McLeod, Marah S.
core +1 more source
IMPACT OF PARENTAL PRESUMPTION ON ADOLESCENTS MENTAL HEALTH AND SUICIDAL THOUGHTS IN TERTIARY INSTITUTIONS IN ANAMBRA STATE-NIGERIA [PDF]
Social Sciences and Education Research ReviewThis study investigated the impact of parental presumption on adolescents' mental health and suicidal thoughts in tertiary institutions in Anambra state-Nigeria.
Nkechi Uzochukwu OKEKE +2 more
doaj +1 more source
Presumption of innocence in peril: a comparative critical perspective
, 2017 This book documents the increasing rate at which the presumption of innocence is being abrogated in criminal process, through use of reverse onus provisions, deeming provisions, and permitting some facts to be assumed from proof of others.
Gray, Anthony
core
The Disability Integration Presumption: Thirty Years Later [PDF]
, 2005 The fiftieth anniversary of the Brown v. Board of Education decision has spurred a lively debate about the merits of “integration.” This article brings that debate to a new context – the integration presumption under the Individuals with Disabilities ...
Colker, Ruth
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Don't Presume the Presumption Has Been Applied Properly
, 2021 In recognition of the humanitarian purpose of the District of Columbia Workers' Compensation Act of 1979, D.C. Code as amended, §32-1501 et seq. and the legislative policy favoring awards even in arguable cases, a claimant is entitled to a presumption of
Jones, Melissa Lin
core +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source