Results 111 to 120 of about 72,936 (296)
The undue influence presumption vs the record title presumption: Marriage of Delaney, 2003 [PDF]
, 2003 This article discusses a California case which held that when an interspousal transaction is to one spouse’s advantage, the Family Code presumption that the transaction was a result of undue influence is trumped by the Evidence Code’s presumption
Bernhardt, Roger
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The “New” Presumption Against Preemption [PDF]
, 2010 Is there or isn\u27t there a “presumption against preemption”? The Supreme Court continues to mention it, but then does, or does not, apply it in a way that helps us understand what it is.
Davis, Mary J.
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Post-EU Accession to the ECHR: The Argument for Why the ECtHR Should Abandon the Bosphorus Doctrine
Utrecht Journal of International and European LawThis article analyses the case law of the ECtHR on the responsibility of the Contracting Parties following from their membership in the EU and the Court’s application of the Bosphorus presumption of equivalent protection over the period 2005–2021.
Šejla Imamović
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Presumption for cancer and infectious disease for firefighters
, 2009 Title from Web page (viewed Mar. 11, 2009).; "February 24, 2009."; Discusses how many states have a rebuttable presumption for firefighters with cancer and infectious diseases under workers' compensation or disability retirement law, and the cost ...
Cummings, Laura.
core +1 more source
A Nuanced Approach to the Disability Integration Presumption [PDF]
, 2007 This paper responds to Ruth Colker, The Disability Integration Presumption: Thirty Years Later, 154 U. PA. L. REV. 789 (2006). I disagree with Professor Colker\u27s proposal that the statutory presumption that children with disabilities be educated to ...
Weber, Mark, Weber, Mark C.
core
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source