Results 61 to 70 of about 236,725 (290)
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley +1 more source
“Late preterm” defines infants born at 340/7 through 366/7 weeks' gestation, which comprise a majority of preterm births. These infants were treated clinically as “near-term” in the past, but recent studies have implied increased morbidities that ...
Ming-Luen Tsai +7 more
doaj +1 more source
VANCOMYCIN PHARMACOKINETICS IN PRETERM INFANTS [PDF]
[corrected] The objective of the present study was to evaluate the kinetic disposition of vancomycin in preterm infants with emphasis on the apparent volume of distribution, biological half-life, and total body clearance as well as whether their variations cause significant modification of the trough plasma concentration of the drug, depending on the ...
Machado, Jose Kleber Kobol +4 more
openaire +4 more sources
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang +14 more
wiley +1 more source
Background: Infants exposed prenatally to drugs of substance use are at increased risk for seizures, strabismus, feeding difficulty, and neurodevelopmental delays. Exposed preterm infants may have additional morbidities related to prematurity.
Subhash Puthuraya +5 more
doaj +1 more source
Neonatal morbidities and developmental delay in moderately preterm-born children [PDF]
BACKGROUND AND OBJECTIVE: Children born moderately preterm (32-35(6/7) weeks' gestation) are at increased risk of both neonatal morbidities and developmental delays in early childhood.
Bocca-Tjeertes, I.F. +4 more
core +2 more sources
Systematic review and network meta-analysis with individual participant data on cord management at preterm birth (iCOMP): study protocol [PDF]
Introduction Timing of cord clamping and other cord management strategies may improve outcomes at preterm birth. However, it is unclear whether benefits apply to all preterm subgroups.
Andersson, Ola +25 more
core +3 more sources
Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang +12 more
wiley +1 more source
Evaluation of Glucagon-Like Peptide 1 (GLP-1) Levels and Oxidative Stress in Preterm Infants
Background and Objective: Glucagon-like peptide 1 (GLP-1) has anti-diabetic, antioxidant and anti-inflammatory properties that change under different conditions. This peptide is known as a therapeutic target in diabetes and obesity. The aim of this study
E Abbasi +6 more
doaj
Cefoperazone Pharmacokinetics in Preterm Infants [PDF]
The elimination pharmacokinetics of cefoperazone, a new cephalosporin, were studied in 15 preterm infants ranging in gestational age from 32 to 36 weeks and in postnatal age from 1 to 6 days. The infants received a single dose of either 50 or 250 mg of cefoperazone per kg by intravenous infusion.
J A, Bosso, G M, Chan, J M, Matsen
openaire +2 more sources

