Results 81 to 90 of about 545,325 (314)

Cortical pain responses in human infants [PDF]

open access: yes, 2006
Despite the recent increase in our understanding of the development of pain processing, it is still not known whether premature infants are capable of processing pain at a cortical level.
Meek, J   +6 more
core  

Precision medicine in paediatrics: Progress and priorities

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain   +3 more
wiley   +1 more source

Comparison of cervical vestibular evoked myogenic potentials between late preterm and term infants

open access: yesThe Turkish Journal of Pediatrics, 2012
Recent investigations have shown that late preterm infants have increased risk for attention deficit hyperactivity disorder, neurosensory impairment, and emotional, behavior and learning problems.
Ayşe Ecevit   +6 more
doaj  

VANCOMYCIN PHARMACOKINETICS IN PRETERM INFANTS [PDF]

open access: yesClinics, 2007
[corrected] The objective of the present study was to evaluate the kinetic disposition of vancomycin in preterm infants with emphasis on the apparent volume of distribution, biological half-life, and total body clearance as well as whether their variations cause significant modification of the trough plasma concentration of the drug, depending on the ...
Machado, Jose Kleber Kobol   +4 more
openaire   +4 more sources

Spanish population-study shows that healthy late preterm infants had worse outcomes one year after discharge than term-born infants

open access: yes, 2018
Aim: This study assessed the risks associated with healthy late preterm infants and healthy term-born infants using national hospital discharge records.
Cristina Fernández-Pérez   +7 more
core   +1 more source

Analysis of clinical investigation (device) initial submissions received by the Medicines and Healthcare products Regulatory Agency between January 2022 and December 2025

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse clinical investigation‐device initial submissions received by the MHRA between January 2022 and December 2025. Methods Data on submissions were extracted from the clinical investigations unit data bank; software as medical devices were not included. The predefined primary end‐point was submission type.
Andrea Manfrin   +7 more
wiley   +1 more source

Unlocking the first year: Immunologic, hematologic, and lung health challenges in premature infants

open access: yesPediatrics and Neonatology
Background: Data on the development of immune, hematologic, and lung function in preterm infants beyond the early postnatal period are limited. This study aimed to determine whether these systems in preterm infants mature to levels comparable to full ...
Sui-Ling Liao   +9 more
doaj   +1 more source

Prevalence of pregnancy and birth outcomes following biologic exposure in immune‐mediated inflammatory diseases: A population‐based study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Almost 5% of pregnancies are affected by immune‐mediated inflammatory diseases (IMIDs). As treatments become available, understanding their use during pregnancy is important. We aimed to describe maternal, pregnancy and infant outcomes among IMID pregnancies exposed to biologic therapies. Methods Using the Merative™ MarketScan® Commercial Database,
Leah K. Flatman   +3 more
wiley   +1 more source

Population pharmacokinetics of levetiracetam in term neonates with hypoxic–ischemic encephalopathy and therapeutic hypothermia: The LEVNEONAT‐1 study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim This study aimed to describe the pharmacokinetics (PK) of levetiracetam (LEV) in term neonates treated for neonatal seizures secondary to hypoxic–ischemic encephalopathy (HIE). Methods Fifteen neonates were included and received a loading dose ranging from 30 to 60 mg/kg followed by eight maintenance doses corresponding to one‐fourth of the loading
Léo Mimram   +9 more
wiley   +1 more source

Retrospective Comparative Analysis of Neonatal Mortality and Morbidity in Preterm Singleton and Multiple Births -Single Center Experience-

open access: yesGlobal Pediatric Health
Objective. To compare mortality and major neonatal morbidities between singleton preterm infants and preterm infants of multiple gestations born
Mohammad Alhasoon MD   +6 more
doaj   +1 more source

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