Results 31 to 40 of about 410,516 (265)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
BMC ChemistryProlonged exposure to ultraviolet (UV) irradiation and microbial contamination correlated to the environmental pollution and ozone layer depletion caused serious health concerns.
Sahar A. El-Kholy +2 more
doaj +1 more source
Foods, 2021 The present research studied the influence of blanching and microwave pretreatment of seeds on the quality of pomegranate seed oil (PSO) extracted by cold pressing. Pomegranate seeds (cv.
Tafadzwa Kaseke +2 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Scientific ReportsIn this study, La co-doped SrMnO₃ (LSM) perovskite nanomaterials with varying La contents (0.0–2.0 wt%) were synthesized via a solid-state method and evaluated for visible-light-driven photocatalytic degradation of methylene blue (MB).
E. R. Sheha +3 more
doaj +1 more source
Dairy Manure Digestate Age Increases Ultrasound Disintegration Efficiency at Low Specific Energies
Energies, 2021 Substantial insight into the effect of ultrasound disintegration on the changes in biochemical parameters of manure digestate and digestate age is needed to understand the potential of digestate treatment.
Matthijs H. Somers +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Applied SciencesPhosphorus, an essential rare element in aquatic ecosystems, plays a key role in maintaining ecosystem balance. However, excess phosphorus leads to eutrophication and algal proliferation.
Jiajie Wang +9 more
doaj +1 more source
Energies, 2023 Bioethanol is the most widely used alternative transportation fuel to petrol. Bioethanol is considered a clean, renewable, and environmentally friendly fuel that can contribute to climate change mitigation, decreased environmental pollution, and enhanced
Sunčica Beluhan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source