Results 121 to 130 of about 3,580,896 (295)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The contribution of genetics to the understanding and management of cardiomyopathies: Part 2
Cardiomyopathies may present as a manifestation of various inherited syndromes. Recognizing the rarity and diagnostic challenges of syndromic and metabolic cardiomyopathies is crucial, as their identification holds significant implications for targeted ...
Isabel Cardoso +13 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Estimating the prevalence of osteoporosis in Australia [PDF]
This report presents information about the prevalence and impact of osteoporosis in Australians aged 50 and over. Summary Osteoporosis, a common condition among older people, causes bones to become weak.
core
Cognitive Improvement After Stroke: Prevalence and Trend During the First Three Months
Introduction: With similar estimates at 3 and 12 months after stroke, 4 out of 10 individuals have cognitive impairment that does not match the criteria for dementia.
Maede Sadat Etesami +5 more
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Multiple Chemical Sensitivity: an Italian prevalence multicentric survey
BackgroundMultiple Chemical Sensitivity (MCS) is a multisystem environmental disorder triggered by exposure to chemical agents at concentrations below toxicological thresholds.
Giovanni Genovese +8 more
doaj +1 more source
Introduction. As a result of the COVID-19 pandemic that swept the whole world in 2020, the level and structure of morbidity changed, the “center of gravity” of adult mortality shifted towards infectious diseases.
V. M. Kuraeva +2 more
doaj

