Results 111 to 120 of about 6,866,993 (305)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

[News Clip: Fire prevention]

open access: yes, 1956
Video footage from the WBAP-TV station in Fort Worth, Texas, covering a news story about a fire prevention program in Dallas.
WBAP-TV (Television station : Fort Worth, Tex.)
core  

The effects of expected prosocial outcome, promotion focus and prevention focus on prosocial willingness.

open access: yes, 2016
The effects of expected prosocial outcome, promotion focus and prevention focus on prosocial willingness.
Fengqiu Xiao (3337188)   +5 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Using essential elements to select, adapt, and evaluate violence prevention approaches [PDF]

open access: yes
The mission of the Centers for Disease Control and Prevention\u2019s (CDC) Division of Violence Prevention is to prevent injuries, deaths, and other health consequences that result from violence.

core  

Zika-prevention behaviors explored during focus group discussions.

open access: yes, 2020
Zika-prevention behaviors explored during focus group discussions.
Ryanne Fujita-Conrads (8544714)   +7 more
core   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Therapist's guide to evidence-based relapse prevention /

open access: yes, 2007
Describes the evidence-based approaches to preventing relapse of major mental and substance-related disorders. Therapist's Guide to Evidence-based Relapse Prevention combines the theoretical rationale, empirical data, and the practical "how-to" for ...
Witkiewitz, Katie., Marlatt, G. Alan.
core  

The effects of expected prosocial outcome, promotion focus and prevention focus on prosocial behavior.

open access: yes, 2016
The effects of expected prosocial outcome, promotion focus and prevention focus on prosocial behavior.
Fengqiu Xiao (3337188)   +5 more
core   +1 more source

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