Results 121 to 130 of about 6,866,993 (305)

The effect of parental regulatory focus on the loneliness stigma of college children

open access: yesBMC Public Health
Background The present study aimed to examine the relationship between regulatory focus and loneliness stigma, as well as the intergenerational transmission of the two.
Zhiguang Fan   +3 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Integrating the ESM usage and work engagement for employee agility performance: based on regulatory focus theory

open access: yesBMC Psychology
This present research aims to clarify the intricate conjunction of enterprise social media (ESM) utilization and employee agility with a main focus on uncovering the underlying mechanisms that work through the mediating influence of work engagement and ...
Yilinna Bao   +3 more
doaj   +1 more source

[Dengue prevention: focus on information].

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2004
The first three months of 2002 witnessed a dengue epidemic in the State of Rio de Janeiro. At that time, health authorities encouraged community participation in the elimination of vector breeding sites. For this campaign, a great quantity of information about the disease was extensively publicized in order to guide the population's preventive action ...
Márcia de Freitas, Lenzi   +1 more
openaire   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

STDs [PDF]

open access: yes
Sexually Transmitted Disease Surveillance 2011 presents statistics and trends for sexually transmitted diseases (STDs) in the United States through 2011.
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (U.S.) Division of STD Prevention.
core  

Suicide Prevention Impact Assessment Toolkit

open access: yes, 2020
This Toolkit provides practical guidance and information for policy-makers in government departments about suicide prevention and how to integrate suicide prevention into policy-making functions.
HSE National Office for Suicide Prevention
core  

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