Results 91 to 100 of about 202,953,608 (275)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The prevention and control of dengue after Typhoon Haiyan
Western Pacific Surveillance and Response, 2015 Objective: Many of the areas in the Philippines affected by Typhoon Haiyan are endemic for dengue; therefore, dengue prevention was a priority in the initial post-disaster risk assessment. We describe the dengue prevention and response strategies applied
Charito Aumentado +10 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Sanitary Policies, Development and Community in Argentina during the 60’s
Revista Ciencias de la Salud, 2014 Objective: This article aims at reviewing the ideas resulting from the medical knowledge related to the design and implementation of the health policies prevailing in Argentina during the 60’s.
Karina Inés Romacciotti
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Small business environmental compliance self-assessment guide a compliance tool for small business.
, 2006 Title from PDF cover (viewed Aug. 24, 2006).; "This guide was produced by: OhioEPA ... Office of Compliance Assistance and Pollution Prevention (OCAPP)"--P.
Ohio EPA. Office of Compliance Assistance and Pollution Prevention.
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ohio Environmental Protection Agency resource guide
, 2006 Title from PDF cover (viewed Aug. 24, 2006).; "This guide was produced by: OhioEPA ... Office of Compliance Assistance and Pollution Prevention (OCAPP)"--P.
Ohio EPA. Office of Compliance Assistance and Pollution Prevention.
core
Malaria JournalBackground Qualified malaria diagnosis competency has contributed to the great achievement of malaria elimination in China. After eliminating malaria, it is still critical to the prevention of re-establishment of malaria transmission in China. This study
He Yan +3 more
doaj +1 more source