Results 101 to 110 of about 461,645 (274)

The Use of Theater to Restore Intergenerational Relationships and Knowledge Transfer in Africa: A Narrative Review

open access: yesForum: Qualitative Social Research
Intergenerational knowledge transfer (IGKT) remains a significant challenge for northern Ugandan communities following 25-years of civil war, displacement, and continued strife in the region. In this narrative review, we explore what is known in relation
Stéphanie Caron-Roy   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Knowledge, attitude and practice levels regarding malaria among the Semai sub-ethnic indigenous Orang Asli communities in Pahang, Peninsular Malaysia: a stepping stone towards the prevention of human malaria re-establishment

open access: yesMalaria Journal
In Malaysia, despite a decline in cases, malaria remains a major public health concern, especially among the vulnerable indigenous people (i.e. Orang Asli) in remote areas. Effective preventive and control measures require an evidence-based understanding of their knowledge, attitudes, and practices (KAP) regarding malaria.
Luqman Samsudin   +10 more
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

International Centre for Reproductive Health (ICRH): an international multidisciplinary centre of excellence in the field of reproductive health [PDF]

open access: yes, 2011
The International Centre for Reproductive Health (ICRH) was established by Prof. dr. Marleen Temmerman in the aftermath of the UN Conference on Population and Development in Cairo in 1994. This conference called for worldwide action to improve the sexual
Claeys, Patricia   +4 more
core   +1 more source

Asymptomatic/submicroscopic Plasmodium vivax infection: A systematic review and META-analysis on the hidden challenge for preventing re-establishment of malaria transmission

open access: yesParasite Epidemiology and Control
BACKGROUND: Plasmodium vivax is not only the second most prevalent cause of malaria worldwide, but also the second leading cause of imported malaria in China. This poses a significant threat to preventing the re-establishment of malaria transmission, as the competent vector (Anopheles sinensis) suitable for vivax malaria transmission is widely ...
Wang, Siqi   +4 more
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Prevention or Control: Optimal Government Policies for Invasive Species Management [PDF]

open access: yes
We present a conceptual, but empirically applicable, model for determining the optimal allocation of resources between exclusion and control activities for managing an invasive species with an uncertain discovery time.
Eiswerth, Mark E.   +3 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Labour Administration Reforms in China [PDF]

open access: yes, 2013
[Excerpt] This publication provides an explanation of the comprehensive labour administration system in China, including its recent advances, with emphasis on its public services functions, such as public employment, labour inspection and social ...
Casale, Giuseppe, Zhu, Changyou
core   +1 more source

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