Results 131 to 140 of about 202,953,608 (275)

SUBVERSIVE FLORI.CULTURES. Ecological manoeuvres from the re-existing South

, 2017
The article deals with the need to approach a decolonial critique of the notion of nature, both in its theoretical and methodological dimension, since it has been clearly reified by Western scientific knowledge to sustain inequalities of power or the ...
Romero Caballero, Belén
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Mandatory surveillance of bacteremia conducted by automated monitoring

Frontiers in Public Health
Except for a few countries, comprehensive all-cause surveillance for bacteremia is not part of mandatory routine public health surveillance. We argue that time has come to include automated surveillance for bacteremia in the national surveillance systems,
Kåre Mølbak, Kåre Mølbak, Christian Østergaard Andersen, Christian Østergaard Andersen, Ram B. Dessau, Ram B. Dessau, Ram B. Dessau, Svend Ellermann-Eriksen, Sophie Gubbels, Thøger Gorm Jensen, Jenny Dahl Knudsen, Brian Kristensen, Lisbeth Lützen, John Coia, Bente Ruth Scharvik Olesen, Mette Pinholt, Flemming Scheutz, Ute Wolff Sönksen, Kirstine K. Søgaard, Marianne Voldstedlund   +19 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Anthrax outbreak: exploring its biological agents and public health implications

Frontiers in Tropical Diseases
The (re)emergence of several infectious zoonoses underlines the need for the re-evaluation of the transmission patterns and key players responsible for effective inter-species transfer of diseases.
Seto C. Ogunleye, Mercy M. Olorunshola, Kolapo A. Fasina, Abdullahi T. Aborode, Olalekan C. Akinsulie, Abimbola Amoo, Boluwatife J. Olatoye, Akeem Bakare, Mariam A. Lawal, Oluwabori Adekanye, Ezemba C. Chinyere   +10 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

A bill to be entitled an act relating to the establishment of an advisory panel to assist with a study regarding the prevention of wrongful convictions.

, 2009
Bill introduced by the Texas House of Representatives relating to the establishment of an advisory panel to assist with a study regarding the prevention of wrongful ...
Texas. Legislature. House of Representatives.
core  

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source