Results 131 to 140 of about 461,645 (274)

Kenya must wake up to the threat of cryptic Anopheles species and their impact on residual malaria transmission

open access: yesJournal of Vector Borne Diseases
Malaria remains a major health problem in Kenya despite the huge efforts put in place to control it. The non-relenting malaria threat has partly been attributed to residual malaria transmission driven by vectors that cannot effectively be controlled by ...
Eunice A Owino
doaj   +1 more source

The Specificity of the Changes in the Lithuanian Health Tourism Services Industry [PDF]

open access: yes, 2014
Purpose of the article: Even if the health tourism is one of the niche tourisms, it demonstrates successful growth comparing to the general tourism, other niches sectors, such as eco, medical, sport, adventure and other forms of tourism.
Langvinienė, Neringa
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Design and Establishment of an Integrated Safety and Preventive Maintenance System for Improving Safety Indexes

open access: yesSalāmat-i kār-i Īrān, 2014
Design and Establishment of an Integrated Safety andPreventive Maintenance System for Improving Safety Indices   Background and aims: Accident analysis shows that one of the main reasons of accidents is non-integration of maintenance units with safety ...
I Mohammadfam   +3 more
doaj  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Reducing Biological Risks to Security: International Policy Recommendations for the Obama Administration [PDF]

open access: yes, 2009
Summarizes discussions among biotechnology and life sciences experts on the risks of bioterrorism and threats to public health and agriculture.

core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Anti-adhesive agents in tendon repair: mechanisms, preclinical evidence, clinical challenges, and future perspectives—a narrative review

open access: yesJournal of Orthopaedic Surgery and Research
Tendon injuries constitute a significant challenge to musculoskeletal health, comprising approximately 50% of all related injuries in the United States and resulting in considerable treatment expenditures.
Mona Kadkhodaei   +5 more
doaj   +1 more source

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