Results 41 to 50 of about 683,936 (256)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Dental findings in patients with West syndrome: A report of two cases

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2014
West syndrome a rare, severe form of epilepsy occurs in early infancy. It is characterized by a triad consisting of infantile spasms that occurs in clusters, arrest of psychomotor development and hypsarrhythmia on electroencephalogram.
Amit Khatri   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

House arrest: concept and essence. [PDF]

open access: yes, 2019
En el año 2001, una nueva medida preventiva en forma de arresto domiciliario se introdujo en la Ley de Procedimiento Penal de la Federación de Rusia; sin embargo, la ley no define el concepto de "arresto domiciliario", pero esta deficiencia se llena en ...
Larisa Potapova.   +3 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Evaluation of chemo-preventive efficacy of Ficus religiosa latex extract by flow cytometry analysis and gene expression studies performed by RT-PCR in various cell lines

open access: yesFuture Journal of Pharmaceutical Sciences, 2021
Background An extract of Ficus religiosa latex has been previously found to possess potent pharmacological activity with high antioxidant content phytochemical.
L. Saida   +2 more
doaj   +1 more source

Use of House Arrest In The Context of the Respecting the Constitutional Rights of an Individual in Russia [PDF]

open access: yes, 2018
The authors analyze the selection of preventive measures in the form of house arrest in Russian criminal procedures on the basis of universal and European standards of guaranteeing respect for individual rights. The article states that the application of
Afanasieva, Svetlana, 2365999   +1 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Recourse against Decisions to Apply or Extend Pre-Trial Detention

open access: yesACROSS
According to Article 5 of the European Convention on Human Rights, “everyone deprived of his liberty by arrest or detention shall have the right to take proceedings before a court so that the court may decide within a short time on the lawfulness of his
Iurie ODAGIU, Ghennadi EPURE
doaj   +2 more sources

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