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The molecular architecture of cell cycle arrest
Molecular Systems Biology, 2022 The cellular decision governing the transition between proliferative and arrested states is crucial to the development and function of every tissue. While the molecular mechanisms that regulate the proliferative cell cycle are well established, we know ...
Wayne Stallaert +10 more
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Acanthamoeba induces cell-cycle arrest in host cells [PDF]
Journal of Medical Microbiology, 2004 Acanthamoeba can cause fatal granulomatous amoebic encephalitis (GAE) and eye keratitis. However, the pathogenesis and pathophysiology of these emerging diseases remain unclear. In this study, the effects of Acanthamoeba on the host cell cycle using human brain microvascular endothelial cells (HBMEC) and human corneal epithelial cells (HCEC) were ...
Sissons, J. +5 more
openaire +4 more sources
Cell cycle arrest of cardiomyocytes in the context of cardiac regeneration [PDF]
Frontiers in Cardiovascular MedicineThe limited capacity of adult mammalian cardiomyocytes to undergo cell division and proliferation is one of the key factors contributing to heart failure.
Qingling Xu +8 more
doaj +2 more sources
Growth inhibition by fusidic acid in cervical, thyroid, and breast carcinoma cell lines [PDF]
Obstetrics & Gynecology Science, 2023 Objective We investigated the effects of fusidic acid (FA) on human cervical, thyroid, and breast carcinoma cell lines to determine the potential usefulness of FA in cancer treatment.
Jin Young Kim +5 more
doaj +1 more source
Cell Reports, 2021 Summary: The formation of new vessels requires a tight synchronization between proliferation, differentiation, and sprouting. However, how these processes are differentially activated, often by neighboring endothelial cells (ECs), remains unclear.
Ayelet Jerafi-Vider +8 more
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Respiratory syncytial virus matrix protein induces lung epithelial cell cycle arrest through a p53 dependent pathway. [PDF]
PLoS ONE, 2012 Respiratory syncytial virus (RSV) is the major cause of viral respiratory infections in children. Our previous study showed that the RSV infection induced lung epithelial cell cycle arrest, which enhanced virus replication.
Tao Bian +3 more
doaj +1 more source
FGF19 induces the cell cycle arrest at G2-phase in chondrocytes
Cell Death Discovery, 2023 Fibroblast growth factor 19 (FGF19) has appeared as a new possible avenue in the treatment of skeletal metabolic disorders. However, the role of FGF19 on cell cycle progression in skeletal system is poorly understood.
Hao Chen +6 more
doaj +1 more source
A Mini-Review on Cell Cycle Regulation of Coronavirus Infection
Frontiers in Veterinary Science, 2020 Coronaviruses are widespread in nature and infect humans, mammals and poultry. They cause harm to humans and animals. Virus-mediated cell cycle arrest is an essential strategy for viral survival and proliferation in the host cells. A clarification system
Mingjun Su +5 more
doaj +1 more source
Bifurcation in cell cycle dynamics regulated by p53 [PDF]
, 2014 We study the regulating mechanism of p53 on the properties of cell cycle dynamics in the light of the proposed model of interacting p53 and cell cycle networks via p53.
Alam, Md. Jahoor +3 more
core +5 more sources
CRIF1 interacting with CDK2 regulates bone marrow microenvironment-induced G0/G1 arrest of leukemia cells. [PDF]
PLoS ONE, 2014 BACKGROUND: To assess the level of CR6-interacting factor 1 (CRIF1), a cell cycle negative regulator, in patients with leukemia and investigate the role of CRIF1 in regulating leukemia cell cycle.
Qian Ran +7 more
doaj +1 more source