Acanthamoeba induces cell-cycle arrest in host cells [PDF]
Journal of Medical Microbiology, 2004 Acanthamoeba can cause fatal granulomatous amoebic encephalitis (GAE) and eye keratitis. However, the pathogenesis and pathophysiology of these emerging diseases remain unclear. In this study, the effects of Acanthamoeba on the host cell cycle using human brain microvascular endothelial cells (HBMEC) and human corneal epithelial cells (HCEC) were ...
Sissons, J. +5 more
openaire +4 more sources
Blocking variant surface glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation. [PDF]
PLoS ONE, 2009 BackgroundThe African trypanosome Trypanosoma brucei is covered with a dense layer of Variant Surface Glycoprotein (VSG), which protects it from lysis by host complement via the alternative pathway in the mammalian bloodstream.
Terry K Smith +9 more
doaj +3 more sources
Cell Cycle Arrest by Supraoptimal Temperature in the Alga Chlamydomonas reinhardtii
Cells, 2019 Temperature is one of the key factors affecting growth and division of algal cells. High temperature inhibits the cell cycle in Chlamydomonas reinhardtii.
Vilém Zachleder +3 more
doaj +2 more sources
Monitoring cell cycle distributions in MCF-7 cells using near-field photothermal microspectroscopy. [PDF]
, 2005 Microspectroscopic techniques such as Fourier transform infrared (FTIR) have played an important role in "fingerprinting" the biochemical composition of cellular components.
Hewitt, Rebecca +4 more
core +5 more sources
Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFβ cell cycle arrest [PDF]
, 2007 Background TGFβ is critical to control hepatocyte proliferation by inducing G1-growth arrest through multiple pathways leading to inhibition of E2F transcription activity.
Dunbar, Donald R +14 more
core +4 more sources
CRIF1 interacting with CDK2 regulates bone marrow microenvironment-induced G0/G1 arrest of leukemia cells. [PDF]
PLoS ONE, 2014 BACKGROUND: To assess the level of CR6-interacting factor 1 (CRIF1), a cell cycle negative regulator, in patients with leukemia and investigate the role of CRIF1 in regulating leukemia cell cycle.
Qian Ran +7 more
doaj +1 more source
Role for Ceramide in Cell Cycle Arrest [PDF]
Journal of Biological Chemistry, 1995 The dependence of some cell types on serum factors for growth may represent a powerful, but poorly studied, model for antimitogenic pathways. In this study, we examine ceramide as a candidate intracellular mediator of serum factor dependence. In Molt-4 leukemia cells, serum withdrawal caused a significant arrest in cell cycle progression (80% of cells ...
S, Jayadev +7 more
openaire +2 more sources
An Antimicrobial Peptide Induces FIG1-Dependent Cell Death During Cell Cycle Arrest in Yeast
Frontiers in Microbiology, 2018 Although most antibiotics act on cells that are actively dividing and non-dividing cells such as in microbe sporulation or cancer stem cells represent a new paradigm for the control of disease.
Vladimir J. Arellano +9 more
doaj +1 more source
Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase [PDF]
, 2014 Upon DNA damage, cell cycle progression is temporally blocked to avoid propagation of mutations. While transformed cells largely maintain the competence to recover from a cell cycle arrest, untransformed cells past the G1/S transition lose mitotic ...
Jaiswal, H. +9 more
core +1 more source
eLife, 2019 In the fungus Ustilago maydis, sexual pheromones elicit mating resulting in an infective filament able to infect corn plants. Along this process a G2 cell cycle arrest is mandatory. Such as cell cycle arrest is initiated upon the pheromone recognition in
Paola Bardetti +4 more
doaj +1 more source