LncRNAs of Saccharomyces cerevisiae bypass the cell cycle arrest imposed by ethanol stress.
PLoS Computational Biology, 2022 Ethanol alters many subsystems of Saccharomyces cerevisiae, including the cell cycle. Two ethanol-responsive lncRNAs in yeast interact with cell cycle proteins, and here, we investigated the role of these RNAs in cell cycle.
Lucas Cardoso Lázari +3 more
doaj +1 more source
Regrowth resistance: low-level platinum resistance mediated by rapid recovery from platinum-induced cell-cycle arrest [PDF]
, 2009 The H69CIS200 and H69OX400 cell lines are novel models of low-level platinum drug resistance developed from H69 human small cell lung cancer cells with eight 4-day treatments of 200 ng/ml cisplatin or 400 ng/ml oxaliplatin respectively. A recovery period
Ross Davey +3 more
core +2 more sources
Gene copy number and cell cycle arrest [PDF]
Physical Biology, 2005 The cell cycle is an orderly sequence of events which ultimately lead to the division of a single cell into two daughter cells. In the case of DNA damage by radiation or chemicals, the damage checkpoints in the $G_{1}$ and $G_{2}$ phases of the cell cycle are activated. This results in an arrest of the cell cycle so that the DNA damage can be repaired.
Ghosh, Bhaswar, Bose, Indrani
openaire +3 more sources
Cip1 tunes cell cycle arrest duration upon calcineurin activation [PDF]
, 2022 Cells exposed to environmental stress arrest the cell cycle until they have adapted to their new environment. Cells adjust the length of the arrest for each unique stressor, but how they do this is not known.
Benanti, Jennifer A, Flynn, Mackenzie J
core +1 more source
Sophisticated framework between cell cycle arrest and apoptosis induction based on p53 dynamics. [PDF]
PLoS ONE, 2009 The tumor suppressor, p53, regulates several gene expressions that are related to the DNA repair protein, cell cycle arrest and apoptosis induction, which activates the implementation of both cell cycle arrest and induction of apoptosis.
Hiroyuki Hamada +6 more
doaj +1 more source
Nek family of kinases in cell cycle, checkpoint control and cancer [PDF]
, 2011 Early studies in lower Eukaryotes have defined a role for the members of the NimA related kinase (Nek) family of protein kinases in cell cycle control. Expansion of the Nek family throughout evolution has been accompanied by their broader involvement in ...
Haider Nasir +15 more
core +1 more source
Digital holographic microscopy for non-invasive monitoring of cell cycle arrest in L929 cells.
PLoS ONE, 2014 Digital holographic microscopy (DHM) has emerged as a powerful non-invasive tool for cell analysis. It has the capacity to analyse multiple parameters simultaneously, such as cell- number, confluence and phase volume.
Maria Falck Miniotis +2 more
doaj +1 more source
Current Issues in Molecular Biology, 2023 Cancer cells are characterised by uncontrolled cell proliferation; however, some of them can temporarily arrest their cell cycle at the G0 or G1 phase, which could contribute to tumour heterogeneity and drug resistance.
Magdalena Kluska +2 more
doaj +1 more source
ERCC1 expression and RAD51B activity correlate with cell cycle response to platinum drug treatment not DNA repair [PDF]
, 2008 Background: The H69CIS200 and H69OX400 cell lines are novel models of low-level platinum-drug resistance. Resistance was not associated with increased cellular glutathione or decreased accumulation of platinum, rather the resistant cell lines have a cell
Davey, Ross +3 more
core +2 more sources
Cell cycle–arrested cells know the right time [PDF]
Cell Cycle, 2016 In order to form functional organs, it is essential to regulate the proliferation rate of progenitor cells as well as their differentiation to generate an ordered series of cell types.
Ayano, Kawaguchi, Fumio, Matsuzaki
openaire +2 more sources