Results 31 to 40 of about 6,610,084 (246)
Cell Cycle Arrest is a Conserved Function of Norovirus VPg Proteins
Viruses, 2019 Murine norovirus (MNV) viral protein genome-linked (VPg) manipulates the cell cycle to induce a G0/G1 arrest and gain a beneficial replication environment.
Alice McSweeney +2 more
doaj +1 more source
Cell Cycle Arrest by Kynurenine in Lens Epithelial Cells [PDF]
Investigative Opthalmology & Visual Science, 2008 Indolemine 2,3-dioxygenase (IDO)-mediated oxidation of tryptophan produces kynurenines (KYNs), which may play a role in cataract formation. The molecular mechanisms by which KYNs cause cellular changes are poorly understood. The effects of KYNs on mouse lens epithelial cells by overexpression of human IDO were investigated.Lens epithelial cells (mLECs)
Maneesh, Mailankot +6 more
openaire +2 more sources
A regulatory module controlling stress-induced cell cycle arrest in Arabidopsis
eLife, 2019 Cell cycle arrest is an active response to stresses that enables organisms to survive under fluctuating environmental conditions. While signalling pathways that inhibit cell cycle progression have been elucidated, the putative core module orchestrating ...
Naoki Takahashi +6 more
doaj +1 more source
Light‐Controlled Cell‐Cycle Arrest and Apoptosis [PDF]
Angewandte Chemie, 2020 AbstractCell‐cycle interference by small molecules has widely been used to study fundamental biological mechanisms and to treat a great variety of diseases, most notably cancer. However, at present only limited possibilities exist for spatio‐temporal control of the cell cycle. Here we report on a photocaging strategy to reversibly arrest the cell cycle
Edgar Uhl +4 more
openaire +3 more sources
Ecotoxicology and Environmental Safety, 2023 Hydroquinone (HQ), a well-known carcinogenic agent, induces oxidative stress, cell cycle arrest, apoptosis, and malignant transformation. As an antioxidant actor, the nuclear factor erythroid 2-related factor 2 (Nrf2) drives adaptive cellular protection ...
Lin Chen +7 more
doaj +1 more source
Cell cycle control and its modulation in HPV infected cells [PDF]
, 2010 A key effect of human papillomavirus (HPV) infection is to disrupt the normal cell cycle in order to subvert the cellular DNA replication machinery. Morphologically, condylomata induced by high and low risk HPV types cannot be distinguished and many ...
Lyman, Rachel C.
core +2 more sources
Irreversibility of cellular senescence: dual roles of p16INK4a/Rb-pathway in cell cycle control
Cell Division, 2007 The retinoblastoma (Rb) tumor suppressor gene product, pRb, has an established role in the implementation of cellular senescence, the state of irreversible G1 cell cycle arrest provoked by diverse oncogenic stresses.
Hara Eiji, Ohtani Naoko, Takahashi Akiko
doaj +1 more source
Cell cycle arrest is not senescence
Aging, 2011 DNA damaging agents and radiation, cytotoxins and anti-cancer drugs, telomere erosion and cytokines, culture shock and mitogenic stimuli, oncogenes and tumor suppressors can induce both cell cycle arrest and cellular senescence. Due to this semi-coincidence, senescence is confused with cell cycle arrest, or even more misleadingly, with growth ...
openaire +2 more sources
Microarray analysis of cell cycle gene expression in adult human corneal endothelial cells. [PDF]
PLoS ONE, 2014 Corneal endothelial cells (ECs) form a monolayer that controls the hydration of the cornea and thus its transparency. Their almost nil proliferative status in humans is responsible, in several frequent diseases, for cell pool attrition that leads to ...
Binh Minh Ha Thi +11 more
doaj +1 more source
Analysis of cell cycle arrest in adipocyte differentiation [PDF]
Oncogene, 1999 Confluent 3T3-L1 preadipocytes differentiate to adipocytes in the presence of insulin, dexamethasone, and isobutylmethylxanthine (IDI). A transient increase of DNA synthesis is induced in 3T3-L1 cells 18 h after addition of IDI, followed by an arrest in the G1 phase of the cell cycle.
M, Reichert, D, Eick
openaire +2 more sources