Results 41 to 50 of about 1,886,210 (293)
Régisseur d’œuvres : enjeux d’un métier émergent et perspectives de professionnalisation
Curatorial functions, born with the modern museum’s emergence during the eighteenth century and in particular with the nascent concepts of inventorying and cataloguing collections, are organically linked to the figure of the person in charge of drawing ...
Sophie Daynes-Diallo +2 more
doaj +1 more source
Rethinking preventive conservation: Recent examples
The past few decades have seen an increasing awareness of the potential socioeconomical and environmental impact of investment in Cultural Heritage (CH). Preserving CH is not only an obligation to sustain and transmit it to the future generation but is also a driver of sustainable growth. Here, recently concluded projects are taken in consideration for
Lourenço, Paulo B. +3 more
openaire +2 more sources
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Organiser les masses : le traitement des archives photographiques du journal L’Humanité
The photo collection of the newspaper L’Humanité, published by the French communist party, was deposited at the departmental archives of Seine-Saint-Denis in 2003. It comprises more than two million pictures.
Joël Clesse, Maxime Courban
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
SIMULATION OF PREVENTIVE CONSERVATION IN A MUSEUM BUILDING - Deliverable D6.3
This deliverable reports on the work carried out in Task 6.3 of WP6 (Simulation of preventive conservation in a museum building), which concerns microclimate control, simulated for a hangar selected in D6.1, designed for preventive conservation of ...
Fiser Jaromir
core +1 more source
Report covers Fiscal Year 2007 and 2008, with planned activities listed for Fiscal Year 2009.<br>Continues title: Soil conservation in Kansas which previously was continued by: Conservation in ...
Kansas. State Conservation Commission
core +1 more source

