Results 121 to 130 of about 1,687,971 (294)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Preventive maintance plan for SKF Latin Trade SAS equipment

open access: yesDyna
This research presents the design and implementation of the preventive and predictive maintenance plan developed for the seven polishing machines of the Swedish multinational SKF, of the LSB (Large Size Bearing) line.
Danilo Andrés González-López   +1 more
doaj   +1 more source

A Simulation Model for Machine Efficiency Improvement Using Reliability Centered Maintenance: Case Study of Semiconductor Factory

open access: yesModelling and Simulation in Engineering, 2014
The purpose of this study was to increase the quality of product by focusing on the machine efficiency improvement. The principle of the reliability centered maintenance (RCM) was applied to increase the machine reliability.
Srisawat Supsomboon   +1 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Determination of a model of preventive maintenance of special purpose vehicles

open access: yesVojnotehnički Glasnik
Introduction/purpose: The aim of this paper is to obtain quantitative and qualitative indicators of vehicle condition and reliability based on operational data which can be used to determine the optimal periodicity of preventive maintenance for special ...
Stojko Lj. Biočanin   +3 more
doaj   +1 more source

On the integrated Production, Inventory and Preventive Maintenance Problem in manufacturing systems with backorder

open access: yes, 2009
International audienceThe integrated Production, Inventory and Preventive Maintenance Problem (PIPMP) is concerned with coordinating production, inventory and preventive maintenance operations to meet customer demand with the aim of minimising costs. The
Gharbi, Ali   +2 more
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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