Results 111 to 120 of about 431,604 (298)

STRATEGI MEMINIMASI BIAYA PERAWATAN UNIT LUFFING CRANE 01 DI PT PELABUHAN INDONESIA III (persero) CABANG TANJUNG EMAS SEMARANG [PDF]

open access: yes, 2017
PT Pelabuhan Indonesia III (persero) atau lebih dikenal dengan sebutan Pelindo III merupakan salah satu badan usaha milik negara (BUMN) yang bergerak dalam bidang jasa pelayanan operator terminal pelabuhan.
DIAH, RAHAYU PUNGKY
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Analisa Sistem Perawatan Komponen Bearing Bottom Roller Dan V Belt Mesin Ring Frame Ry-5 Pada Departemen Spinning II a (Di PT Danliris Surakarta) [PDF]

open access: yes, 2007
PT Danliris Surakarta merupakan Perusahaan textil dengan salah satu produk yang dihasilkan adalah benang, yang diproduksi melalui mesin-mesin Blowing, Carding, Drawing, Lap Form, Combing, Flyer, Ring Spinning dan Winder.
Pujotomo, D. (Darminto), S, R. K. (Rama)
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Preventive maintance plan for SKF Latin Trade SAS equipment

open access: yesDyna
This research presents the design and implementation of the preventive and predictive maintenance plan developed for the seven polishing machines of the Swedish multinational SKF, of the LSB (Large Size Bearing) line.
Danilo Andrés González-López   +1 more
doaj   +1 more source

A Simulation Model for Machine Efficiency Improvement Using Reliability Centered Maintenance: Case Study of Semiconductor Factory

open access: yesModelling and Simulation in Engineering, 2014
The purpose of this study was to increase the quality of product by focusing on the machine efficiency improvement. The principle of the reliability centered maintenance (RCM) was applied to increase the machine reliability.
Srisawat Supsomboon   +1 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Determination of a model of preventive maintenance of special purpose vehicles

open access: yesVojnotehnički Glasnik
Introduction/purpose: The aim of this paper is to obtain quantitative and qualitative indicators of vehicle condition and reliability based on operational data which can be used to determine the optimal periodicity of preventive maintenance for special ...
Stojko Lj. Biočanin   +3 more
doaj   +1 more source

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