Results 101 to 110 of about 1,687,971 (294)
The Economic Design of and Control Charts with Preventive Maintenance and Increasing Hazard Rate
, 2010 [[abstract]]Develops the joint economic designs of • and S2 control charts under four operating policies to monitor the process in a situation where the occurrence of the assignable cause follows a general distribution with an increasing hazard rate. The
Huan‐Neng Chiu;Bo‐Shi Huang
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The technical systems preventive maintenance trade-off model
Vojnotehnički Glasnik, 1996 A complex technical system preventive maintenance model based on a 'trade-off' between maximum availability and cost-effectiveness criterions was developed.
Svetomir Minić +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The modern approach to preventive maintenance of parasitic diseases
Российский паразитологический журнал, 2016 It is offered sanitary-parasitological and veterinary-sanitary model of preventive maintenance of parasitic diseases of people and animals which approbation has resulted in the high effect expressing in reduction of number of cases of new infections in ...
G. R. Bajramgulova +5 more
doaj
Optimal burn-in and preventive maintenance warranty strategies with time-dependent maintenance costs
, 2013 This article considers the determination of the optimal burn-in time, the degree of preventive maintenance, and the preventive maintenance interval (or, equivalently, the number of preventive maintenance actions) for warranted products with time ...
Shafiee, Mahmood +10 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Statistical analysis of corrective and preventive maintenance in medical equipment
, 2022 Maintenance of medical equipment plays an important role in ensuring the healthcare quality so that the care can be conducted with minimal risk. Preventive maintenance is performed to maintain the equipment in satisfactory operating condition, while ...
von Schewelov, Linn
core +2 more sources