Results 101 to 110 of about 431,604 (298)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Lifetime multi-objective optimization of maintenance of existing steel structures [PDF]

open access: yes, 2006
In this paper, the lifetime performance of deteriorating structures, defined by their time dependent condition index and reliability index, is analyzed. The effect of preventive and essential maintenance actions on performance and cost in predicted, and ...
Cruz, Paulo J. S.   +2 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Detection of structural deterioration and associated airline maintenance problems [PDF]

open access: yes
Airline operations involving the detection of structural deterioration and associated maintenance problems are discussed. The standard approach to the maintenance and inspection of aircraft components and systems is described.
Henniker, H. D., Mitchell, R. G.
core   +1 more source

Usulan Jadwal Perawatan Preventif Mesin HGF di Stasiun Puteran Pabrik Gula [PDF]

open access: yes, 2008
The HGF (High Grade Fugal) Machine is one of the machines which often failed in The Sugar Factory XYZ. Brake Shoes and Belt drive are critical components of HGF Machine. The Management already used corrective maintenance policy where the maintenance only
Nugroho, Ari   +2 more
core  

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

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