Results 111 to 120 of about 739,700 (305)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Boundary Effects on Population Dynamics in Stochastic Lattice Lotka-Volterra Models

, 2017
We investigate spatially inhomogeneous versions of the stochastic Lotka-Volterra model for predator-prey competition and coexistence by means of Monte Carlo simulations on a two-dimensional lattice with periodic boundary conditions.
Chen, Sheng, Heiba, Bassel, Täuber, Uwe C.   +2 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Feeding habits of otters living on three moors in the Pannonian ecoregion (Hungary) [PDF]

, 2006
Diet composition and feeding habits of Eurasian otters (Lutra lutra) living on three moors (Balata, Nagyberek and Feherviz) in Hungary were studied over two years using spraint analysis (n = 199, 503 and 3 15 samples from the three moors, respectively ...
Lanszki, József, Lanszkiné Széles, Gabriella   +1 more
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Exploitation dynamics of fish stocks

, 2006
I address the question of the fluctuations in fishery landings. Using the fishery statistics time-series collected by the Food and Agriculture Organization of the United Nations since the early 1950s, I here analyze fishing activities and find two ...
Amaral, Axtell, Bjørnstad, Bjørnstad, Botsford, Buldyrev, Caddy, Chave, Conklin, D'Ancona, D'Ancona, Dixon, Ehrhardt, Frisch, Garcia, Garcia, Gordon, Grainger, Higgins, Hilborn, Hiro-Sato Niwa, Hsieh, Johnstone, Keitt, Keitt, Laherrère, Lee, Lotka, Matia, Matsuda, Matsuda, May, May, Niwa, Niwa, Pauly, Pauly, Pauly, Plerou, Smith, Sprague, Stanley, Stanley, Symes, Sæther, Takeuchi, Turchin, Volterra, Watson, Weibull, Weisbuch, Widom, Widom, Wilson, Zipf   +54 more
core   +1 more source

Trophic Cascades and Habitat Suitability in Udanti Sitnadi Tiger Reserve: Impacts of Prey Depletion and Climate Change on Predator Prey Dynamics

This study investigates the trophic cascades and habitat suitability in Udanti Sitnadi Tiger Reserve (USTR), highlighting the roles of apex predators, subordinate predators, and prey species in maintaining ecosystem balance. Using the Trophic Species Distribution Model (SDM), we explored prey-predator interactions and habitat suitability, revealing ...
Basak, Krishnendu, Chaudhuri, Chiranjib, Suraj, M, Ahmed, Moiz   +3 more
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Decline in condition of northern bluefin tuna (Thunnus thynnus) in the Gulf of Maine [PDF]

, 2007
The northern bluefin tuna (Thunnus thynnus) is a highly mobile apex predator in the Gulf of Maine. Despite current stock assessments that indicate historically high abundance of its main prey, Atlantic herring (Clupea harengus), commercial fishermen have
Campbell , Robert, Cooper, Andrew B., Golet, Walter J., Lutcavage, Molly   +3 more
core