Results 101 to 110 of about 566,493 (267)

Missing Data Gap Imputation Methods in Electroencephalogram (EEG) Signals: A Systematic Scoping Review

Sensors
Objective: Electroencephalogram (EEG) measures electrophysiological activity in the cerebral cortex and is broadly used across diagnostic, research, and clinical contexts.
Tobias Bergmann, Michael Movshovich, Yushu Shao, Julia Ryznar, Xue Nemoga-Stout, Izabella Marquez, Isuru Herath, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Noah Silvaggio, Rakibul Hasan, Kevin Y. Stein, Hina Shaheen, Jaewoong Moon, Frederick A. Zeiler   +14 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The Price of Decentralisation

SSRN Electronic Journal, 2010
This paper develops a model for analysing problems related to centralisation and decentralisation. The model is of the new economic geography type, in which there are agglomeration gains in cities but not in rural areas. These gains are counteracted by residential preferences.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Bridge helix of Cas12a is an allosteric regulator of R-loop formation and RuvC activation

Nature Communications
CRISPR-Cas12a, an RNA-based DNA targeting system, is widely used for genome editing and biomarker detection. To mitigate the off-target DNA cleavage of Cas12a, we previously developed a Francisella novicida Cas12a variant (FnoCas12aKD2P) by introducing ...
Chhandosee Ganguly, Swarmistha Devi Aribam, Alberto Monteiro dos Santos, Lindsie Martin, Leonard M. Thomas, Yihan Shao, Rakhi Rajan   +6 more
doaj   +1 more source

RFID Sensor with Integrated Energy Harvesting for Wireless Measurement of dc Magnetic Fields

Sensors
High-voltage direct-current (HVdc) transmission lines are gaining more attention as an integral part of modern power system networks. Monitoring the dc current is important for metering and the development of dynamic line rating control schemes. However,
Shijie Fu, Greg E. Bridges, Behzad Kordi
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The Utah Manipulation and Locomotion of Large Objects (MeLLO) Data Library

Bioengineering
The purpose of this paper is to provide researchers with a description of a data library representing human interaction with medium- to large-sized objects in everyday life. The library includes motion capture data characterizing human and object motion,
Nathaniel G. Luttmer, Nathan I. Baum, Josue Flores-Gonzalez, John M. Hollerbach, Mark A. Minor   +4 more
doaj   +1 more source