A Conjoint Analysis of Consumer Preferences on Shiitake Mushrooms: A Case Study of the Republic of Korea. [PDF]
FoodsLee C, Kim K.
europepmc +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Is price associated with the quality of medicines? Evidence from active pharmaceutical ingredient testing in Nigeria. [PDF]
PLoS OneMontás MC, Anyakora C, Maffioli EM.
europepmc +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
A Call to Recognize the Integral Role of Physician Associates and Nurse Practitioners in Modern Health Care: Editorial. [PDF]
J Particip MedPrice A, Price K.
europepmc +1 more source
"أثر إدارة تبويب التدفقات النقدية على مخاطر انهيار أسعار الأسهم: دراسة تحليلية على مستوى القطاعات للشركات المقيدة في البورصة المصرية" The Effect of Cash Flow Classification Shifting on Stock Price Crash Risk: A Sector-Based Analysis of Companies Listed on the Egyptian Stock Exchange [PDF]
نسمة محمود محمود أبو العنين +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Global mechanisms to improve affordability of high-priced medicines: the role of the WHO model lists of essential medicines. [PDF]
J Pharm Policy PractJenei K.
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source