Results 61 to 70 of about 9,641 (300)

The Role of Intracellular Interactions in the Collective Polarization of Tissues and its Interplay with Cellular Geometry

, 2019
Planar cell polarity (PCP), the coherent in-plane polarization of a tissue on multicellular length scales, provides directional information that guides a multitude of developmental processes at cellular and tissue levels.
Mani, Madhav, Shadkhoo, Shahriar
core   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Robust Asymmetric Localization of Planar Polarity Proteins Is Associated with Organization into Signalosome-like Domains of Variable Stoichiometry. [PDF]

, 2016
In developing epithelia, the core planar polarity proteins physically interact with each other and localize asymmetrically at opposite cell ends, forming intercellular complexes that link the polarity of neighboring cells.
Aigouy, Amonlirdviman, Axelrod, Bastock, Bienz, Burak, Butler, Chen, Chien, Chiu, Chiu, Cho, Coffman, Damle, Das, Devenport, Devenport, Djiane, Douglass, Feiguin, Goodrich, Goswami, Jenny, Jenny, Johnston, Kishida, Le Garrec, Li, Lin, McGill, Schamberg, Shimada, Simons, Struhl, Strutt, Strutt, Strutt, Strutt, Strutt, Strutt, Tauriello, Tree, Usui, Vinson, Wallingford, Wasserscheid, Wolff, Wu, Wu, Yap   +49 more
core   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Electron Microscopic Study of Epidermal Prickle Cells

Journal of Investigative Dermatology, 1952
The introduction of the electron microscope by Knoll and Ruska (1) in 1931 has led to the development of new technics for the examination of biological material with this instrument. The preparation of very thin tissue sections of the thickness of 34 o micron and thinner has been one such recent development.
Laden, Edward L., Erickson, John O., Armen, Dorothy   +2 more
openaire   +2 more sources

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Integrated metabolomic and transcriptomic analysis to uncover the developmental mechanism of Zanthoxylum armatum prickles

Industrial Crops and Products
Zanthoxylum armatum is a commercially valuable plant species widely cultivated in China; however, its dense coverage of sharp prickles is a serious challenge for the agricultural production and fruit harvesting of Z. armatum.
Shanbo Chen, Yang Cao, Chi Zhao, Sha Wang, Chenghao Zhang, Zhiqing Zhang, Liu Chen, Wei Peng, Lihua Wang, Yongqing Guo, Zhiwu Yang, Shijing Feng, Yinchun Jin   +12 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells [PDF]

, 2019
The gingival epithelium is a physical and immunological barrier to the microbiota of the oral cavity, which interact through soluble mediators with the immune cells that patrol the tissue at the gingival epithelium.
Bradshaw, David, Brown, Jason L., Butcher, John, Culshaw, Shauna, Delaney, Chris, Johnston, William, Khan, Shaz, Rajendran, Ranjith, Ramage, Gordon   +8 more
core   +4 more sources