Results 51 to 60 of about 341,402 (293)
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Prim-SNPing: a primer designer for cost-effective SNP genotyping
BioTechniques, 2009 Many kinds of primer design (PD) software tools have been developed, but most of them lack a single nucleotide polymorphism (SNP) genotyping service.
Hsueh-Wei Chang +6 more
doaj +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
European Journal of Psychotraumatology, 2017 Background: Depression is a common psychopathological outcome following military deployment. Previous studies have reported differing rates of post-deployment depression, indicating that the toll of war differs across missions.
Karen-Inge Karstoft +2 more
doaj +1 more source
Application of PRIM for understanding patterns in carbon dioxide model-observation differences [PDF]
Atmospheric Chemistry and PhysicsReducing uncertainties in regional carbon balances requires a better understanding of CO2 transport in synoptic weather systems. Here, we apply the Patient Rule Induction Method (PRIM), a data-mining method to identify high-density regions for a target ...
T. Gerken +3 more
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
A Random PRIM Based Algorithm for Interpretable Classification and Advanced Subgroup Discovery
AlgorithmsMachine-learning algorithms have made significant strides, achieving high accuracy in many applications. However, traditional models often need large datasets, as they typically peel substantial portions of the data in each iteration, complicating the ...
Rym Nassih, Abdelaziz Berrado
doaj +1 more source
Al-Khwarizmi: Jurnal Pendidikan Matematika dan Ilmu Pengetahuan Alam, 2018 : This study aims to be considered in the planning of cabling on fishermen housing in the city of Palopo. And used as a comparison in determining the minimum distance in the electricity network.
Riswan Riswan
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
FEBS Open Bio, 2022 The initiation of Okazaki fragment synthesis during cellular DNA replication is a crucial step for lagging strand synthesis, which is carried out by the primase function of DNA polymerase α‐primase (Pol‐prim).
Nichodemus O. Onwubiko +3 more
doaj +1 more source