Results 111 to 120 of about 18,376 (235)

A humanized mouse model for sequestration of Plasmodium falciparum sexual stages and in vivo evaluation of gametocytidal drugs [PDF]

, 2016
The development of new drugs to disrupt malaria transmission requires the establishment of an in vivo model to address the biology of Plasmodium falciparum sexual stages (gametocytes).
Cisteró, Pau, Duffier, Yoann, Dupuy, Florian, Fiette, Laurence, Jouvion, Gregory, Lavazec, Catherine, Lorthiois, Audrey, Mayor Aparicio, Alfredo Gabriel, Mazier, Dominique, Moreno Sabater, Alicia   +9 more
core   +4 more sources

Infection of Anopheles darlingi fed on patients infected with Plasmodium vivax before and during treatment with chloroquine plus primaquine in Costa Marques, Rondônia, Brazil

Memorias do Instituto Oswaldo Cruz, 1992
Five patients with asexual and sexual parasites of Plasmodium vivax were treated orally with 600 mg chloroquine diphosphate (hour 0) followed with 300 mg at 8, 24 and 48 h later.
Terry A. Klein, Mauro S. Tada, Jose B. P. Lima, Amazonia Toda Tang   +3 more
doaj   +1 more source

Subdoses de primaquina associadas a recaídas de malária vivax em pacientes com peso elevado : relato de dois casos no Distrito Federal [PDF]

, 2010
São apresentados dois casos de pacientes com malária por Plasmodium vivax que apresentaram recaídas após tratamento com medicamentos em doses indicadas pelo Ministério da Saúde.
Deckers, Fernando Augusto Lopes, Luz, Francisco das Chagas de Oliveira, Santos, João Barberino, Tauil, Pedro Luiz   +3 more
core   +2 more sources

Pharmacokinetics of primaquine in man. II. Comparison of acute vs chronic dosage in Thai subjects. [PDF]

, 1985
Stephen A. Ward, GW Mihaly, Geoffrey Edwards, S Looareesuwan, RE Phillips, Pornthep Chanthavanich, D A Warrell, ML Orme, AM Breckenridge   +8 more
openalex   +1 more source

Improving the radical cure of vivax malaria (IMPROV): a study protocol for a multicentre randomised, placebo-controlled comparison of short and long course primaquine regimens. [PDF]

, 2015
BACKGROUND: Plasmodium vivax malaria is a major cause of morbidity and recognised as an important contributor to mortality in some endemic areas. The current recommended treatment regimen for the radical cure of P.
IMPROV Study Group
core   +1 more source

A RARE GLIMPSE AT THE EFFICACY OF PRIMAQUINE [PDF]

, 2007
J. Kevin Baird
openalex   +1 more source

Artemisinin-naphthoquine combination versus chloroquine-primaquine to treat vivax malaria: an open-label randomized and non-inferiority trial in Yunnan Province, China [PDF]

, 2013
Hui Liu, Henglin Yang, Jian-Wei Xu, Jiazhi Wang, Ren-hua Nie, Chunfu Li   +5 more
openalex   +1 more source

Rationale for short course primaquine in Africa to interrupt malaria transmission

Malaria Journal, 2012
Following the recent successes of malaria control in sub-Saharan Africa, the gametocytocidal drug primaquine needs evaluation as a tool to further reduce the transmission of Plasmodium falciparum malaria. The drug has scarcely been used in Africa because
Eziefula Alice C, Gosling Roly, Hwang Jimee, Hsiang Michelle S, Bousema Teun, von Seidlein Lorenz, Drakeley Chris   +6 more
doaj   +1 more source

Primaquine for preventing relapse in people with Plasmodium vivax malaria treated with chloroquine [PDF]

, 2013
Gawrie NL Galappaththy, Prathap Tharyan, Richard Kirubakaran   +2 more
openalex   +1 more source

Burden and clinical characteristics of recurrent Plasmodium vivax infections, and impact of primaquine for radical cure: a systematic scoping review in India

Frontiers in Malaria
BackgroundIndia accounts for the bulk of Plasmodium vivax burden in South East Asia. Primaquine (PQ) is the only currently available drug for treating relapses in P. vivax malaria.
Loick Pradel Kojom Foko, Vineeta Singh
doaj   +1 more source