Results 91 to 100 of about 3,657 (146)

Primaquine for Prevention of Malaria in Travelers [PDF]

, 2003
An expanding risk and range of endemic malaria threatens travelers. Primaquine is an old drug recently demonstrated to offer effective prophylaxis. Clinical trials conducted in Indonesia, Kenya, and Colombia showed that a primaquine base (30 mg per day ...
Hoffman, Stephen L., Baird, JK, D. J. Fryauff, Hoffman, SL, Baird, John, Fryauff, DJ, J. Kevin Baird, Baird, J. Kevin, S. L. Hoffman, Fryauff, David J.   +9 more
core   +1 more source

Optimally timing primaquine treatment to reduce Plasmodium falciparum transmission in low endemicity Thai-Myanmar border populations

Malaria Journal, 2009
Background Effective malaria control has successfully reduced the malaria burden in many countries, but to eliminate malaria, these countries will need to further improve their control efforts.
Hungerford Laura L, Maneeboonyang Wanchai, Thanyavanich Nipon, Yimsamran Surapon, Singhasivanon Pratap, Klein Eili Y, Lawpoolsri Saranath, Maguire James H, Smith David L   +8 more
doaj   +1 more source

Dihydroartemisinin-piperaquine versus chloroquine to treat vivax malaria in Afghanistan: an open randomized, non-inferiority, trial. [PDF]

, 2010
BACKGROUND: Afghanistan's national guidelines recommend chloroquine for the treatment of Plasmodium vivax infection, the parasite responsible for the majority of its malaria burden. Chloroquine resistance in P. vivax is emerging in Asia.
Faizullah Kaker, Dondorp Arjen M, Sasithon Pukrittayakamee, Dondorp, AM, Sue Lee, Woodrow, CJ, Singhasivanon Pratap, Pukrittayakamee Sasithon, Pukrittayakamee, S, Pratap Singhasivanon, Arjen M Dondorp, Nicholas PJ Day, Day, NP, Day Nicholas PJ, Charles J Woodrow, White Nicholas J, Lee, SJ, Singhasivanon, P, Awab, GR, Kaker Faizullah, Imwong Mallika, Dondorp, Adrianus, Nicholas J White, Mallika Imwong, Imwong, Mallika, Imwong, M, Day, Nicholas, White, NJ, White, Nicholas, Awab Ghulam, Ghulam Awab, Woodrow Charles J, Lee Sue, Kaker, F   +33 more
core   +1 more source

Single dose primaquine policies in American countries.

, 2018
All countries use single dose primaquine (mostly 0.75 mg/kg) as policy for falciparum treatment (shown in blue) except for French Guiana (red), with no G6PD deficiency testing required before primaquine administration.
Elizabeth A. Ashley (237173), Nicholas J. White (35779), Judith Recht (3750991)   +2 more
core   +1 more source

Burden and clinical characteristics of recurrent Plasmodium vivax infections, and impact of primaquine for radical cure: a systematic scoping review in India

Frontiers in Malaria
BackgroundIndia accounts for the bulk of Plasmodium vivax burden in South East Asia. Primaquine (PQ) is the only currently available drug for treating relapses in P. vivax malaria.
Loick Pradel Kojom Foko, Vineeta Singh
doaj   +1 more source

Consideration of ethics in primaquine therapy against malaria transmission.

, 2010
Millions of people receive primaquine against sexual plasmodia responsible for malaria transmission. These gametocytes cause no symptoms and do not threaten the host, but they infect mosquitoes and threaten the community.
Baird, JK, J. Kevin Baird, Baird, John, Surjadjaja, C., Surjadjaja, C, Claudia Surjadjaja, Baird, J.K.   +6 more
core   +1 more source

Clinical aspects of hemolysis in patients with P. vivax malaria treated with primaquine, in the Brazilian Amazon

Brazilian Journal of Infectious Diseases, 2010
This report describes the development of hemolysis in eighteen glucose-6-phosphate dehydrogenase deficient patients treated for Plasmodium vivax malaria with chloroquine and primaquine.
Wilson M. Ramos Júnior, José F.J. Sardinha, Mônica R.F. Costa, Marli S. Santana, Maria G.C. Alecrim, Marcus V.G. Lacerda   +5 more
doaj   +1 more source

Blood stage antimalarial efficacy of primaquine in Plasmodium vivax malaria.

, 1994
The blood stage antimalarial efficacy of primaquine (0.25 mg of base/kg of body weight/day over 14 days) and chloroquine (25 mg of base/kg over 3 days) were compared in 85 adult Thai men with acute Plasmodium vivax malaria.
R. Clemens, Pukrittayakamee, S, Clemens, R, A. Chantra, Chantra, A, N. J. White, S. Pukrittayakamee, S. Vanijanonta, White, NJ, White, Nicholas, Vanijanonta, S   +10 more
core   +1 more source

Management of vivax malaria with low sensitivity to primaquine

Over the last two decades there have been numerous reports of primaquine failure in the treatment of Plasmodium vivax extending from the Western Pacific to South East Asia, India and Central and South America.
Ajdukiewicz KMB, Ong ELC
core   +5 more sources

Antiproliferative evaluation of various aminoquinoline derivatives

Acta Pharmaceutica, 2019
Four classes of aminoquinoline derivatives were prepared: primaquine ureas 1a–f, primaquine bis-ureas 2a–f, chloroquine fumardiamides 3a–f and mefloquine fumardiamides 4a–f.
Zorc Branka, Rajić Zrinka, Perković Ivana   +2 more
doaj   +1 more source