Results 71 to 80 of about 16,373 (205)
Adherence to Plasmodium vivax malaria treatment in the Brazilian Amazon Region [PDF]
Background Patients' adherence to malaria treatment is an important factor in determining the therapeutic response to anti-malarial drugs. It contributes to the patient's complete recovery and prevents the emergence of parasite resistance to anti ...
Elza A Pereira +2 more
core +2 more sources
Halopithys incurva is a red macroalga distributed across the Mediterranean Sea and North‐East Atlantic, with occasional reports from the Indian Ocean. It exhibits a rich chemical diversity, including isoflavones, bromophenols, MAAs, pigments, phycobiliproteins, primary metabolites, and neuroactive compounds.
Youssra Aalilou +9 more
wiley +1 more source
ABSTRACT Background G6PD deficiency affects about 500 million people worldwide and is prevalent in many malaria‐endemic settings. People with G6PD deficiency are at risk of hemolysis when exposed to certain medications, including 8‐aminoquinoline drugs used to treat Plasmodium vivax malaria.
Flavia Regina Medeiros da Silva +7 more
wiley +1 more source
A reiterative method for calculating the early bactericidal activity of antituberculosis drugs.
Studies of early bactericidal activity (EBA) are important in the rapid evaluation of new antituberculosis drugs. Historically, these have concentrated on the log fall in the viable count in sputum during the first 48 hours of therapy.
Charalambous, Bambos M +2 more
core +1 more source
Reactivity of Blood Samples Spotted onto Filter Papers in the WST-8 Method for Screening of G6PD Deficiency. [PDF]
Deficiency of glucose-6-phosphate dehydrogenase (G6PD) causes acute hemolytic anemia triggered by oxidative drugs such as primaquine. It is therefore essential in malaria-endemic areas for malaria patients to be confirmed for their G6PD activity before ...
Arai, Meiji +3 more
core +1 more source
Bioequivalence of a new coated 15 mg primaquine formulation for malaria elimination
Background With only one 15 mg primaquine tablet registered by a stringent regulatory authority and marketed, more quality-assured primaquine is needed to meet the demands of malaria elimination.
Julie Nguyen Ngoc Pouplin +11 more
doaj +1 more source
Primaquine and Chloroquine Fumardiamides as Promising Antiplasmodial Agents
This paper describes a continuation of our efforts in the pursuit of novel antiplasmodial agents with optimized properties. Following our previous discovery of biologically potent asymmetric primaquine (PQ) and halogenaniline fumardiamides (1−6 ...
Maja Beus +7 more
doaj +1 more source
The enantiomeric resolution of primaquine, quinacrine and tafenoquine antibacterial medicines is described on Chirobiotc R column (150 ×4.6 mm, 5.0 µm). Two eluents used were methanol–acetonitrile-water-triethyl amine in the ratio of 70:10:20:0.1 (I) and
Zeid A. ALOthman +2 more
doaj +1 more source
Strong gametocytocidal effect of methylene blue-based combination therapy against falciparum malaria [PDF]
With the availability of new preventive and curative interventions, global malaria control has been strengthened significantly in recent years. Drugs effective in reducing malaria gametocytaemia might contribute to local elimination and possible long ...
Coulibaly, Boubacar +7 more
core +1 more source
Genomic Insights Into Host Shifts Between Plasmodium vivax and Plasmodium simium in Latin America
ABSTRACT Malaria in Latin America is largely caused by Plasmodium vivax, but the closely related monkey parasite Plasmodium simium has recently been observed in humans, thus raising new public health concerns. By screening 719 monkey samples from five Latin America countries, we identified 23 Plasmodium‐positives.
Margaux J. M. Lefebvre +16 more
wiley +1 more source

