Results 81 to 90 of about 3,657 (146)

Factors affecting primaquine combination treatment in Malaria patients in Selangor, Malaysia

Journal of Pharmacy and Bioallied Sciences, 2017
Introduction: Primaquine is vital for the management of liver-stage Plasmodium vivax and Plasmodium ovale malaria. However, primaquine effectiveness is dependent on various factors and differs between populations.
Norliza Mat Ariffin, Farida Islahudin, Mohd Makmor-Bakry, Endang Kumolosasi, Mohd Hafizi A Hamid   +4 more
doaj   +1 more source

Strong Cross‐Reactivity of Anti–Plasmodium falciparum pLDH Monoclonal Antibodies With Plasmodium malariae pLDH in the Abbott Bioline Malaria Ag P.f/P.f/P.v Rapid Diagnostic Test

Tropical Medicine &International Health, Volume 31, Issue 7, Page 944-952, July 2026.
ABSTRACT Objectives This study aimed to describe the cross‐reactivity of the Abbott Bioline Malaria Ag P.f/P.f/P.v rapid diagnostic test, designed to detect Plasmodium falciparum and P. vivax , with other Plasmodium species, based on the detection of parasite lactate dehydrogenase enzymes.
Gabriel Montoia, Maria Carmen Arroyo Sanchez, Giselle Lima‐Cooper, Maria de Lourdes Rego Neves Farinas, Juliana Inoue, Silvia Maria Di Santi   +5 more
wiley   +1 more source

Estudio piloto de la eficacia y de los efectos sobre los gametocitos del esquema artesunato-mefloquina-primaquina para la malaria por Plasmodium falciparum

Biomédica: revista del Instituto Nacional de Salud, 2009
Introducción. El tratamiento de la malaria por P. falciparum requiere de un esquema seguro, eficaz y de impacto en la transmisión. En 2006, se implementó en Antioquia el esquema artesunato-mefloquina y se adicionó primaquina para eliminar los gametocitos.
Ana María Vásquez, Felipe Sanín, Luis Gonzalo Álvarez, Alberto Tobón, Alexandra Ríos, Silvia Blair   +5 more
doaj   +1 more source

Computational modelling of the pro‐ and antiarrhythmic effects of atrial high rate‐dependent trafficking of small‐conductance calcium‐activated potassium channels

The Journal of Physiology, Volume 604, Issue 13, Page 5355-5377, 1 July 2026.
Abstract figure legend Small‐conductance calcium‐activated potassium (SK) channels are important for atrial repolarization and can be targeted for atrial‐specific antiarrhythmic treatments. We developed a computational model with a calcium sensor to study the effects of increased pacing rate (5 Hz), which enhances SK‐channel gating and forward ...
Stefan Meier, Dobromir Dobrev, Paul G. A. Volders, Jordi Heijman   +3 more
wiley   +1 more source

Bioequivalence of a new coated 15 mg primaquine formulation for malaria elimination

Malaria Journal
Background With only one 15 mg primaquine tablet registered by a stringent regulatory authority and marketed, more quality-assured primaquine is needed to meet the demands of malaria elimination.
Julie Nguyen Ngoc Pouplin, Thoopmanee Kaendiao, Bilal Ahmad Rahimi, Mayur Soni, Hensi Basopia, Darshana Shah, Jitendra Patil, Vyom Dholakia, Yash Suthar, Joel Tarning, Mavuto Mukaka, Walter R. Taylor   +11 more
doaj   +1 more source

Comparative evaluation of efficacy and safety of primaquine sustained-release tablets v/s primaquine conventional tablets in Treatment and prevention of relapse of plasmodium vivax malaria [PDF]

, 2016
Background: Malaria is one of the most important parasitic disease of human. In India 60-65% of infections are due to P.vivax and 35-40% are due to P.falciparum Malaria is an acute, recurrent and sometimes chronic vector borne protozoan disease which has
Kakkar, Shivankan, Gupta, Vishnu Kumar, Verma, Arvind, Yadav, Harsh, Jhalani, Gopal   +4 more
core   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

Phytochemical Analysis, Volume 37, Issue 4, Page 507-535, June 2026.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek, Mesra Aktas, Hale Saybasili, Kutlu O. Ulgen   +3 more
wiley   +1 more source

Ultrastructural alterations in Schistosoma mansoni juvenile and adult male worms after in vitro incubation with primaquine

Memorias do Instituto Oswaldo Cruz
BACKGROUND Praziquantel has been cited as the only drug for treating schistosomiasis. However, concerns over drug resistance have encouraged the search for novel drug leads.
Reem Osama A Kamel, Fatma El-Zahraa Anwar Bayaumy   +1 more
doaj   +1 more source

Infection of Anopheles darlingi fed on patients infected with Plasmodium vivax before and during treatment with chloroquine plus primaquine in Costa Marques, Rondônia, Brazil

Memorias do Instituto Oswaldo Cruz, 1992
Five patients with asexual and sexual parasites of Plasmodium vivax were treated orally with 600 mg chloroquine diphosphate (hour 0) followed with 300 mg at 8, 24 and 48 h later.
Terry A. Klein, Mauro S. Tada, Jose B. P. Lima, Amazonia Toda Tang   +3 more
doaj   +1 more source

Crystal structure of Plasmodium vivax macrophage migration inhibitory factor

Acta Crystallographica Section F, Volume 82, Issue 6, Page 194-200, June 2026.
The production, crystallization and 1.8 Å resolution crystal structure of macrophage migratory inhibitory factor from P. vivax are reported.Plasmodium vivax is a major cause of malaria globally and has recently been transmitted locally in the USA. P. vivax produces homologs of host proteins, including cytokines such as macrophage migration inhibitory ...
Aryana Nair, Matthew Lin, Arav Srivastava, Lijun Liu, Anne Cooper, Kevin Battaile, Elizabeth Harmon, Peter J. Myler, Bart L. Staker, Scott Lovell, Graham Chakafana, Oluwatoyin A. Asojo   +11 more
wiley   +1 more source